Results 191 to 200 of about 17,877 (340)

Potent, Selective, and Brain Penetrant Ether-Linked 2-Aminopyridine Inhibitors of Human Neuronal Nitric Oxide Synthase with Excellent Oral Bioavailability. [PDF]

J Med Chem
Ansari A, Chrzanowski RT, Li H, Hardy CD, Awasthi A, Poulos TL, Silverman RB.   +6 more
europepmc   +1 more source

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Gut microbial metabolite imidazole propionate impairs endothelial cell function and promotes the development of atherosclerosis [PDF]

Vanasa Nageswaran, Alba Carreras, Leander Reinshagen, Katharina R. Beck, Jakob Steinfeldt, Marcus Ståhlman, Pegah Ramezani Rad, J.J. Lim, Elisabeth Strässler, Barbara J. H. Verhaar, Yvonne Döring, Christian Weber, Maximilian König, Elisabeth Steinhagen‐Thiessen, Ilja Demuth, Nicolle Kränkel, David M. Leistner, Max Nieuwdorp, Petra Knaus, Marc Ferrell, Michael Potente, Stanley L. Hazen, Ulf Landmesser, Fredrik Bäckhed, Arash Haghikia   +24 more
openalex   +1 more source

Acute Effects of Topical Methyl Tert–Butyl Ether or Ethyl Propionate on Gallbladder Histology in Animals: A Comparison of Two Solvents for Contact Dissolution of Cholesterol Gallstones [PDF]

, 1992
Oliver Esch, John C. Spinosa, Ronald L. Hamilton, Diane L. Crombie, Claudio D. Schteingart, Joseph F. Rondinone, H B D'Agostino, Jan Lillienau, Alan F. Hofmann   +8 more
openalex   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Structural insights into the recognition of tetrapyrrole substrates by ancestral class II chelatase CfbA. [PDF]

Protein Sci
Ogawa S, Hikita M, Fujishiro T.
europepmc   +1 more source

Alopecic Patches on the Extremities of a Young Man

JEADV Clinical Practice, EarlyView.
Hamad El Hajj, Dima Jeha, Samer Ghosn, Hala Abi Rached Megarbane   +3 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Associations between preservative food additives and type 2 diabetes incidence in the NutriNet-Santé prospective cohort. [PDF]

Nat Commun
Hasenböhler A, Javaux G, Payen de la Garanderie M, Szabo de Edelenyi F, Bourhis L, Agaësse C, De Sa A, Huybrechts I, Pierre F, Coumoul X, Julia C, Kesse-Guyot E, Allès B, Fezeu LK, Hercberg S, Deschasaux-Tanguy M, Cosson E, Tatulashvili S, Chassaing B, Srour B, Touvier M.   +20 more
europepmc   +1 more source

Draft Genome Sequence of Paludibacter jiangxiensis NM7 ^T , a Propionate-Producing Fermentative Bacterium [PDF]

, 2017
Yanling Qiu, Dieter M. Tourlousse, Norihisa Matsuura, Akiko Ohashi, Yuji Sekiguchi   +4 more
openalex   +1 more source