Results 61 to 70 of about 203,215 (259)

Application of Artificial Neural Network in Predicting the Survival Rate of Gastric Cancer Patients [PDF]

Iranian Journal of Public Health, 2011
"nBackground: The aim of this study was to predict the survival rate of Iranian gastric cancer patients using the Cox proportional hazard and artificial neural network models as well as comparing the ability of these approaches in predicting the ...
A Biglarian, E Hajizadeh, A Kazemnejad, MR Zali   +3 more
doaj   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The risk factors of infant mortality in Somalia: evidence from the 2018/2019 Somali health & demographic survey

BMC Pediatrics
Background Globally, infant mortality is one of the major public health threats, especially in low-income countries. The infant mortality rate of Somalia stands at 73 deaths per 1000 live births, which is one of the highest infant death rates in the ...
Dahir Abdi Ali, Nasra Abdulhalim Mohamed, Abdirahman Ibrahim Ismail, Gallad Dahir Hassan   +3 more
doaj   +1 more source

COX PROPORTIONAL HAZARD AND EXPONENTIAL SURVIVAL ANALYSIS IN PATIENTS WITH END-STAGE CHRONIC KIDNEY FAILURE AT BOJONEGORO

Barekeng
End-stage chronic renal failure is a condition that requires long-term treatment such as haemodialysis and poses a serious threat to patient survival.
Nur Silviyah Rahmi, Achmad Rifai, M. Irfan Islami, Annisa Andra Azifa   +3 more
doaj   +1 more source

Goodness-of-fit tests in the Cox proportional hazards model

Communications in Statistics - Simulation and Computation, 2019
We consider a variety of tests for testing goodness-of-fit in a parametric Cox proportional hazards (PH) model and compare their performance.
Marike Cockeran, Simos G. Meintanis, James S. Allison   +2 more
openaire   +4 more sources

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Model Selection Strategy for Cox Proportional Hazards Model

Dhaka University Journal of Science, 2019
Often in survival regression modelling, not all predictors are relevant to the outcome variable. Discarding such irrelevant variables is very crucial in model selection. In this research, under Cox Proportional Hazards (PH) model we study different model selection criteria including Stepwise selection, Least Absolute Shrinkage and Selection Operator ...
Md Jamil Hasan Karami, Fabiha Binte Farooq   +1 more
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source