Results 61 to 70 of about 304,906 (296)

Joint Models for Incomplete Longitudinal Data and Time-to-Event Data

open access: yesMathematics, 2022
Clinical studies often collect longitudinal and time-to-event data for each subject. Joint modeling is a powerful methodology for evaluating the association between these data.
Yuriko Takeda   +2 more
doaj   +1 more source

Geoadditive hazard regression for interval censored survival times [PDF]

open access: yes, 2005
The Cox proportional hazards model is the most commonly used method when analyzing the impact of covariates on continuous survival times. In its classical form, the Cox model was introduced in the setting of right-censored observations.
Kneib, Thomas
core   +4 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A Flexible Link Function for Discrete-Time Duration Models [PDF]

open access: yes, 2014
This paper proposes a discrete-time hazard regression approach based on the relation between hazard rate models and excess over threshold models, which are frequently encountered in extreme value modelling.
Gertheiss, Jan   +2 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Tire demand planning based on reliability and operating environment [PDF]

open access: yesInternational Journal of Mining and Geo-Engineering, 2016
Tires represent a critical spare part in mines. There is a shortage of medium and large tires. In addition, with increased mining activities and the creation of new mines, the demand for tires has increased significantly.
Ali Nouri Qarahasanlou   +4 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Deep learning approach for survival prediction for patients with synovial sarcoma

open access: yesTumor Biology, 2018
Synovial sarcoma is a rare disease with diverse progression characteristics. We developed a novel deep-learning-based prediction algorithm for survival rates of synovial sarcoma patients.
Ilkyu Han   +4 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Modeling and Predicting the Popularity of Online Contents with Cox Proportional Hazard Regression Model [PDF]

open access: yes, 2012
Special Issue on Advances in Web IntelligenceInternational audienceWe propose a general framework which can be used for modeling and predicting the popularity of online contents.
Lee, Jong Gun   +2 more
core   +3 more sources

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