Results 21 to 30 of about 1,821,882 (341)

Methods for non-proportional hazards in clinical trials: A systematic review [PDF]

open access: yesStatistical Methods in Medical Research, 2023
For the analysis of time-to-event data, frequently used methods such as the log-rank test or the Cox proportional hazards model are based on the proportional hazards assumption, which is often debatable.
M. Bardo   +15 more
semanticscholar   +1 more source

Generalized Proportional Reversed Hazards Model [PDF]

open access: yesThe Egyptian Statistical Journal, 2004
Inthis paper, we propose to generalized proportional reversed hazards model by Tsx*,t=[Ts,(X, t)]a, where Tsx*,tis baseline distribution func- tion and a is a positive real number.
M. Kayid, I. Elbatal
doaj   +1 more source

Testing the proportional hazards assumption in cox regression and dealing with possible non-proportionality in total joint arthroplasty research: methodological perspectives and review

open access: yesBMC Musculoskeletal Disorders, 2021
Background Survival analysis and effect of covariates on survival time is a central research interest. Cox proportional hazards regression remains as a gold standard in the survival analysis. The Cox model relies on the assumption of proportional hazards
I. Kuitunen   +4 more
semanticscholar   +1 more source

Using fractional polynomials and restricted cubic splines to model non‐proportional hazards or time‐varying covariate effects in the Cox regression model

open access: yesStatistics in Medicine, 2021
The Cox proportional hazards model is used extensively in clinical and epidemiological research. A key assumption of this model is that of proportional hazards.
P. Austin, Jiming Fang, Douglas S. Lee
semanticscholar   +1 more source

Survival analysis—part 2: Cox proportional hazards model

open access: yesIndian Journal of Thoracic and Cardiovascular Surgery, 2021
Learning objectives: 1. To understand the log-rank test and limitations of the log-rank test in comparing survival between groups. 2. To understand the fundamental concepts of the proportional hazards assumption. 3.
S. Deo, V. Deo, V. Sundaram
semanticscholar   +1 more source

DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network [PDF]

open access: yesBMC Medical Research Methodology, 2016
BackgroundMedical practitioners use survival models to explore and understand the relationships between patients’ covariates (e.g. clinical and genetic features) and the effectiveness of various treatment options. Standard survival models like the linear
Jared Katzman   +5 more
semanticscholar   +1 more source

Regression Models for Lifetime Data: An Overview

open access: yesStats, 2022
Two methods dominate the regression analysis of time-to-event data: the accelerated failure time model and the proportional hazards model. Broadly speaking, these predominate in reliability modelling and biomedical applications, respectively.
Chrys Caroni
doaj   +1 more source

On Cox proportional hazards model performance under different sampling schemes.

open access: yesPLoS ONE, 2023
Cox's proportional hazards model (PH) is an acceptable model for survival data analysis. This work investigates PH models' performance under different efficient sampling schemes for analyzing time to event data (survival data). We will compare a modified
Hani Samawi, Lili Yu, JingJing Yin
doaj   +2 more sources

Interval-Censored Regression with Non-Proportional Hazards with Applications

open access: yesStats, 2023
Proportional hazards models and, in some situations, accelerated failure time models, are not suitable for analyzing data when the failure ratio between two individuals is not constant. We present a Weibull accelerated failure time model with covariables
Fábio Prataviera   +4 more
doaj   +1 more source

Pain and mortality among older adults in Korea [PDF]

open access: yesEpidemiology and Health, 2021
OBJECTIVES With the increasing elderly population with chronic disease, understanding pain and designing appropriate policy interventions to it have become crucial.
Chiil Song, Wankyo Chung
doaj   +1 more source

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