Results 101 to 110 of about 1,576,634 (357)

Identification of glioblastoma gene prognosis modules based on weighted gene co-expression network analysis

BMC Medical Genomics, 2018
Background Glioblastoma multiforme, the most prevalent and aggressive brain tumour, has a poor prognosis. The molecular mechanisms underlying gliomagenesis remain poorly understood.
Pengfei Xu, Jian Yang, Junhui Liu, Xue Yang, Jianming Liao, Fanen Yuan, Yang Xu, Baohui Liu, Qianxue Chen   +8 more
doaj   +1 more source

A Bayesian Semiparametric Temporally-Stratified Proportional Hazards Model with Spatial Frailties.

Bayesian Analysis, 2012
Incorporating temporal and spatial variation could potentially enhance information gathered from survival data. This paper proposes a Bayesian semiparametric model for capturing spatio-temporal heterogeneity within the proportional hazards framework. The
T. Hanson, A. Jara, Luping Zhao
semanticscholar   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Joint application of hybrid iterative reconstruction and adaptive filters on neck‐and‐shoulder CT imaging: A clinical evaluation

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To assess whether the joint application of hybrid iterative reconstruction (HIR) and an adaptive filter (AF) could reduce streak artifacts and improve image quality of neck‐and‐shoulder computed tomography (CT). Methods This study included 96 patients with suspicious neck lesions who underwent a routine nonenhanced scan on a 64‐slice ...
Wenfeng Jin, Yifei Ma, Dan Han, Xiaojie Xie, Weiyuan Zhang, Yan Wu, Guozhi Zhang   +6 more
wiley   +1 more source

A measure of explained risk in the proportional hazards model.

Biostatistics, 2012
A measure of explained risk is developed for application with the proportional hazards model. The statistic, which is called the estimated explained relative risk, has a simple analytical form and is unaffected by censoring that is independent of ...
G. Heller
semanticscholar   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Clinical commissioning of an adaptive radiotherapy platform: Results and recommendations

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Online adaptive radiotherapy platforms present a unique challenge for commissioning as guidance is lacking and specialized adaptive equipment, such as deformable phantoms, are rare. We designed a novel adaptive commissioning process consisting of end‐to‐end tests using standard clinical resources.
Kelly Kisling, Timothy D. Keiper, Daniela Branco, Grace Gwe‐Ya Kim, Kevin L Moore, Xenia Ray   +5 more
wiley   +1 more source

Application of Fractional Polynomial Model for Determining Prognostic Factors Associated with Survival of Patients with Gastric Cancer

مجله اپیدمیولوژی ایران, 2013
Background & Objectives: Cox regression model is one of the statistical methods in survival analysis. The use of smoothing techniques in Cox model makes the more accurate estimates for the parameters.
H Noorkojuri, E Hajizadeh, AR Baghestani, MA Pourhoseingholi   +3 more
doaj  

Modelling Method for Maintenance Decision-Making in Civil Aero Engines Based on Multiple State Parameters

MATEC Web of Conferences, 2017
For airlines, a scientific and effective method for engine maintenance decision-making should be developed for the planning of aero engine maintenance and removal.
Cao Huiling, Wu Zemin, Miao Jiahe
doaj   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source