Results 131 to 140 of about 786,239 (293)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

A Corrected Score Approach for Proportional Hazards Model With Error-Contaminated Covariates Subject to Detection Limits. [PDF]

Stat Med
Song X, Wang CY.
europepmc   +1 more source

Analysis of the Proportional Hazards Model With Sparse Longitudinal Covariates

Journal of the American Statistical Association, 2015

semanticscholar   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Verticox+: vertically distributed Cox proportional hazards model with improved privacy guarantees. [PDF]

Complex Intell Systems
van Daalen F, Smits D, Ippel L, Dekker A, Bermejo I.   +4 more
europepmc   +1 more source

A novel 14-gene signature for overall survival in lung adenocarcinoma based on the Bayesian hierarchical Cox proportional hazards model. [PDF]

Sci Rep, 2022
Sun N, Chu J, Hu W, Chen X, Yi N, Shen Y.   +5 more
europepmc   +1 more source

A Proportional Hazards Regression Model for the Subdistribution with Covariates‐adjusted Censoring Weight for Competing Risks Data

Scandinavian journal of statistics, theory and applications, 2016
Peng He, F. Eriksson, T. Scheike, Mei‐jie Zhang   +3 more
semanticscholar   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

The Impact of Violation of the Proportional Hazards Assumption on the Calibration of the Cox Proportional Hazards Model. [PDF]

Stat Med
Austin PC, Giardiello D.
europepmc   +1 more source

Using Aalen's Linear Hazards Model to Investigate Time-varying Effects in the Proportional Hazards Regression Model

, 2002
D. Hosmer, P. Royston
semanticscholar   +1 more source