The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
THE EFFECT OF CMV INFECTION ON PROGRESSION OF HUMAN-IMMUNODEFICIENCY-VIRUS DISEASE IN A COHORT OF HEMOPHILIC MEN FOLLOWED FOR UP TO 13 YEARS FROM SEROCONVERSION [PDF]
, 1995 The effect of prior infection with cytomegalovirus (CMV) on progression of HIV disease in a cohort of 111 men with haemophilia was studied after 13 years followup.
EMERY, V +5 more
core +1 more source
FEBS Open Bio, EarlyView.d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada +3 more
wiley +1 more source
A transformer model for cause-specific hazard prediction
BMC BioinformaticsBackgroud Modelling discrete-time cause-specific hazards in the presence of competing events and non-proportional hazards is a challenging task in many domains.
Matthieu Oliver +4 more
doaj +1 more source
Sure Joint Screening for High Dimensional Cox's Proportional Hazards Model Under the Case-Cohort Design. [PDF]
J Comput Biol, 2023 Liu Y, Li G.
europepmc +1 more source
Earthing effects on mitochondrial function: ATP production and ROS generation
FEBS Open Bio, EarlyView.In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source
The effects of short-term training measures on the individual unemployment duration in West Germany [PDF]
Short-term training measures are the most important intervention of German active labor market policy in terms of persons promoted. However, evidence on the impacts of programs is missing.
Hujer, Reinhard +2 more
core
ESTIMATION AND INFERENCE FOR EXPOSURE EFFECTS WITH LATENCY IN THE COX PROPORTIONAL HAZARDS MODEL IN THE PRESENCE OF EXPOSURE MEASUREMENT ERROR. [PDF]
Ann Appl Stat, 2023 Peskoe SB +3 more
europepmc +1 more source
The Singularity of the Information Matrix of the Mixed Proportional Hazard Model [PDF]
, 2003 Geert Ridder, Tiemen Woutersen
openalex +1 more source
FEBS Open Bio, EarlyView.Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash +6 more
wiley +1 more source