Results 171 to 180 of about 800,848 (376)

Influence diagnostics for the proportional hazards model [PDF]

, 1990
Lisa A. Weissfeld
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Modeling Survival Analysis in Gastric Cancer Patients Using the Proportional Hazards Model of Cox

مجله اپیدمیولوژی ایران, 2007
Background & Objectives: Cancer has been traditionally regarded as a fatal disease; it is a major public health problem in many countries throughout the world.
B Moghimi Dehkordi, A Rajaeefard, HR Tabatabaee, B Zeighami, A Safaee, Z Tabeie   +5 more
doaj  

Combining symbolic regression with the Cox proportional hazards model improves prediction of heart failure deaths. [PDF]

BMC Med Inform Decis Mak, 2022
Wilstrup C, Cave C.
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

A calibrated Bayesian method for the stratified proportional hazards model with missing covariates. [PDF]

Lifetime Data Anal, 2022
Kim S, Kim JK, Ahn KW.
europepmc   +1 more source

A flexible, computationally efficient method for fitting the proportional hazards model to interval‐censored data

Biometrics, 2016
Lianming Wang, C. McMahan, M. Hudgens, Z. Qureshi   +3 more
semanticscholar   +1 more source

The Singularity of the Efficiency Bound of the Mixed Proportional Hazard Model [PDF]

, 2001
Geert Ridder, Tiemen Woutersen
openalex  

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source