Results 31 to 40 of about 377,632 (286)

An Online Updating Approach for Testing the Proportional Hazards Assumption with Streams of Big Survival Data

open access: yes, 2018
The Cox model, which remains as the first choice in analyzing time-to-event data even for large datasets, relies on the proportional hazards assumption. When the data size exceeds the computer memory, the standard statistics for testing the proportional ...
Schifano, Elizabeth D.   +3 more
core   +1 more source

Partial Orders with Respect to Continuous Covariates and Tests for the Proportional Hazards Model [PDF]

open access: yes, 2008
Several omnibus tests of the proportional hazards assumption have been proposed in the literature. In the two-sample case, tests have also been developed against ordered alternatives like monotone hazard ratio and monotone ratio of cumulative hazards ...
Bhattacharjee, Arnab
core   +3 more sources

Comparison of methods for estimating the attributable risk in the context of survival analysis

open access: yesBMC Medical Research Methodology, 2017
Background The attributable risk (AR) measures the proportion of disease cases that can be attributed to an exposure in the population. Several definitions and estimation methods have been proposed for survival data.
Malamine Gassama   +3 more
doaj   +1 more source

The importance of censoring in competing risks analysis of the subdistribution hazard

open access: yesBMC Medical Research Methodology, 2017
Background The analysis of time-to-event data can be complicated by competing risks, which are events that alter the probability of, or completely preclude the occurrence of an event of interest.
Mark W. Donoghoe, Val Gebski
doaj   +1 more source

A mixed model approach for structured hazard regression [PDF]

open access: yes, 2004
The classical Cox proportional hazards model is a benchmark approach to analyze continuous survival times in the presence of covariate information. In a number of applications, there is a need to relax one or more of its inherent assumptions, such as ...
Fahrmeir, Ludwig, Kneib, Thomas
core   +2 more sources

Tree-augmented Cox proportional hazards models [PDF]

open access: yesBiostatistics, 2005
We study a hybrid model that combines Cox proportional hazards regression with tree-structured modeling. The main idea is to use step functions, provided by a tree structure, to 'augment' Cox (1972) proportional hazards models. The proposed model not only provides a natural assessment of the adequacy of the Cox proportional hazards model but also ...
Su, Xiaogang, Tsai, Chih Ling
openaire   +4 more sources

Time and dose dependency of bone-sarcomas in patients injected with radium-224 [PDF]

open access: yes, 1988
The time course and dose dependency of the incidence of bone-sarcomas among 900 German patients treated with high doses of radium-224 is analysed in terms of a proportional hazards model with a log-normal dependency of time to tumor and a linear ...
A. M. Kellerer   +14 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez   +14 more
wiley   +1 more source

joineR: Joint modelling of repeated measurements and time-to-event data [PDF]

open access: yes, 2012
The joineR package implements methods for analysing data from longitudinal studies in which the response from each subject consists of a time-sequence of repeated measurements and a possibly censored time-toevent outcome.
Diggle, Peter   +5 more
core  

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