Results 41 to 50 of about 209,848 (255)

Causal Interactions in the Proportional Hazards Model [PDF]

Epidemiology, 2011
The paper relates estimation and testing for additive interaction in proportional hazards models to causal interactions within the counterfactual framework. A definition of a causal interaction for time-to-event outcomes is given that generalizes existing definitions for dichotomous outcomes. Conditions are given concerning the relative excess risk due
openaire   +2 more sources

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Fitting The First Birth Interval in Indonesia Using Weibull Proportional Hazards Model

Cauchy: Jurnal Matematika Murni dan Aplikasi, 2018
The first birth interval is one of the indicators of women’s fertility rate. Because in most cases the first birth interval contains censored observations, the only appropriate statistical method to handle such data is survival analysis.
Alfensi Faruk, Endro Setyo Cahyono, Ning Eliyati   +2 more
doaj   +1 more source

Estimation in a Cox Proportional Hazards Cure Model [PDF]

Biometrics, 2000
Summary.Some failure time data come from a population that consists of some subjects who are susceptible to and others who are nonsusceptible to the event of interest. The data typically have heavy censoring at the end of the follow‐up period, and a standard survival analysis would not always be appropriate.
Sy, Judy P., Taylor, Jeremy M. G.
openaire   +4 more sources

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita, Norma Candelaria López Santiago, Claudia Maria García Cuellar, Karla Maldonado Silva, Nancy Reynoso Noverón, Leticia Hernández Cadena   +5 more
wiley   +1 more source

ANALYSIS MULTILEVEL SURVIVAL DATA USING COVARIATE-ADJUSTED FRAILTY PROPORTIONAL HAZARDS MODEL

Media Statistika
Multilevel survival data is time-to-event data with a hierarchical or nested structure. This study aims to model the data using the Covariate-Adjusted Frailty Proportional Hazards method, which is an extension of the Cox proportional hazards model with ...
Krismona Sandelvia, Adhitya Ronnie Effendie   +1 more
doaj   +1 more source

PENERAPAN REGRESI COX PROPORTIONAL HAZARD UNTUK MENDUGA FAKTOR-FAKTOR YANG MEMENGARUHI LAMA MENCARI KERJA

E-Jurnal Matematika, 2013
Survival analysis is a statistical method that accommodates the collection of censored data. One of popular method in survival analysis is the Cox Proportional Hazard Regression.
I GEDE ARI SUDANA, NI LUH PUTU SUCIPTAWATI, LUH PUTU IDA HARINI   +2 more
doaj   +1 more source

Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex, Sean P. Hassan, Helen Benghiat, Liam Herbert, Jennifer Adamski, Shivani Bailey, Claire Esler, Louise Brookes, Molly Bamber, Grace Koudou, Karen Waite, Julie Bennett, Anirban Das, Derek S. Tsang   +13 more
wiley   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Are non-constant rates and non-proportional treatment effects accounted for in the design and analysis of randomised controlled trials? A review of current practice

BMC Medical Research Methodology, 2019
Background Most clinical trials with time-to-event primary outcomes are designed assuming constant event rates and proportional hazards over time. Non-constant event rates and non-proportional hazards are seen increasingly frequently in trials.
Kim Jachno, Stephane Heritier, Rory Wolfe   +2 more
doaj   +1 more source