Results 61 to 70 of about 228,669 (304)
Cox proportional hazards model of fever duration. [PDF]
, 2019 Cox proportional hazards model of fever duration.
Takashi Odagiri (1981429) +7 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Multivariable Cox proportional hazards model for in-hospital mortality. [PDF]
, 2022 Multivariable Cox proportional hazards model for in-hospital mortality.
Jane Cerise (7875311) +6 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Lifetime Prediction of Product Based on Proportional Hazards-Proportional Odds Model in Accelerated Life Testing [PDF]
, 2010 Accelerated life testing can be operated in the designing process of a product to predict the lifetime of the product. The design of the product would be improved if the lifetime prediction value is not acceptable. This paper presents a method to predict
Ting Ting Huang +2 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Properties and inference for proportional Hazard models
Revista Colombiana de Estadística, 2013 We consider an arbitrary continuous cumulative distribution function F(x) with a probability density function f(x) = dF(x)/dx and hazard function h f(x)=f(x)/[1-F(x)]. We propose a new family of distributions, the so-called proportional hazard distribution-function, whose hazard function is proportional to h f(x).
MARTÍNEZ-FLÓREZ, GUILLERMO +2 more
openaire +4 more sources
Competing risk models to estimate the excess mortality and the first recurrent-event hazards [PDF]
, 2011 Background In medical research, one common competing risks situation is the study of different types of events, such as disease recurrence and death. We focused on that situation but considered death under two aspects: "expected death" and "excess death",
Belot Aurélien +14 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
A semiparametric Bayesian proportional hazards model for interval censored data with frailty effects
BMC Medical Research Methodology, 2009 Background Multivariate analysis of interval censored event data based on classical likelihood methods is notoriously cumbersome. Likelihood inference for models which additionally include random effects are not available at all.
Hölzel Dieter +3 more
doaj +1 more source