Results 41 to 50 of about 800,848 (376)

Comparison of methods for estimating the attributable risk in the context of survival analysis

BMC Medical Research Methodology, 2017
Background The attributable risk (AR) measures the proportion of disease cases that can be attributed to an exposure in the population. Several definitions and estimation methods have been proposed for survival data.
Malamine Gassama, Jacques Bénichou, Laureen Dartois, Anne C. M. Thiébaut   +3 more
doaj   +1 more source

Partial Orders with Respect to Continuous Covariates and Tests for the Proportional Hazards Model [PDF]

, 2008
Several omnibus tests of the proportional hazards assumption have been proposed in the literature. In the two-sample case, tests have also been developed against ordered alternatives like monotone hazard ratio and monotone ratio of cumulative hazards ...
Bhattacharjee, Arnab
core   +3 more sources

The importance of censoring in competing risks analysis of the subdistribution hazard

BMC Medical Research Methodology, 2017
Background The analysis of time-to-event data can be complicated by competing risks, which are events that alter the probability of, or completely preclude the occurrence of an event of interest.
Mark W. Donoghoe, Val Gebski
doaj   +1 more source

A mixed model approach for structured hazard regression [PDF]

, 2004
The classical Cox proportional hazards model is a benchmark approach to analyze continuous survival times in the presence of covariate information. In a number of applications, there is a need to relax one or more of its inherent assumptions, such as ...
Fahrmeir, Ludwig, Kneib, Thomas
core   +2 more sources

Tree-augmented Cox proportional hazards models [PDF]

Biostatistics, 2005
We study a hybrid model that combines Cox proportional hazards regression with tree-structured modeling. The main idea is to use step functions, provided by a tree structure, to 'augment' Cox (1972) proportional hazards models. The proposed model not only provides a natural assessment of the adequacy of the Cox proportional hazards model but also ...
Su, Xiaogang, Tsai, Chih Ling
openaire   +4 more sources

An Assessment of the Cox Proportional Hazards Regression Model for Epidemiologic Studies

Risk Analysis, 2018
The basic assumptions of the Cox proportional hazards regression model are rarely questioned. This study addresses whether hazard ratio, i.e., relative risk (RR), estimates using the Cox model are biased when these assumptions are violated.
S. Moolgavkar, E. T. Chang, Heather N. Watson, E. Lau   +3 more
semanticscholar   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Time and dose dependency of bone-sarcomas in patients injected with radium-224 [PDF]

, 1988
The time course and dose dependency of the incidence of bone-sarcomas among 900 German patients treated with high doses of radium-224 is analysed in terms of a proportional hazards model with a log-normal dependency of time to tumor and a linear ...
A. M. Kellerer, C. E. Land, C. W. Mays, CE Land, Committee on the biological effects of ionizing radiations, CW Mays, CW Mays, CW Mays, CW Mays, D Chmelevsky, D. Chmelevsky, H Spiess, H. Spiess, JS Spratt, RR Wick   +14 more
core   +1 more source

Statistical power to detect violation of the proportional hazards assumption when using the Cox regression model

Journal of Statistical Computation and Simulation, 2017
The use of the Cox proportional hazards regression model is wide-spread. A key assumption of the model is that of proportional hazards. Analysts frequently test the validity of this assumption using statistical significance testing.
P. Austin
semanticscholar   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source