Results 41 to 50 of about 349,638 (336)

Model Regresi Cox Proportional Hazards Pada Data Lama Studi Mahasiswa (Studi Kasus Di Fakultas Sains Dan Matematika Universitas Diponegoro Semarang Mahasiswa Angkatan 2009) [PDF]

, 2014
High education has important role to increase the intellectual life of the nation and the development of natural sciences and technology by producing the quality graduates. The quality graduates just need 48 month to finish the study.
Hutahaean, L. P. (Landong), Mukid, M. A. (Moch), Wuryandari, T. (Triastuti)   +2 more
core  

Are non-constant rates and non-proportional treatment effects accounted for in the design and analysis of randomised controlled trials? A review of current practice

BMC Medical Research Methodology, 2019
Background Most clinical trials with time-to-event primary outcomes are designed assuming constant event rates and proportional hazards over time. Non-constant event rates and non-proportional hazards are seen increasingly frequently in trials.
Kim Jachno, Stephane Heritier, Rory Wolfe   +2 more
doaj   +1 more source

Efficient Estimation and Inference in the Proportional Odds Model for Survival Data

Mathematics, 2022
In modeling time-to-event data with long-term survivors, the proportional hazards model is widely used for its easy and direct interpretation as well as the flexibility to accommodate the past information and allow time-varying predictors.
Xifen Huang, Chaosong Xiong, Tao Jiang, Junfeng Lu, Jinfeng Xu   +4 more
doaj   +1 more source

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

Population Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

A Resampling Method to Improve the Prognostic Model of End-Stage Kidney Disease: A Better Strategy for Imbalanced Data

Frontiers in Medicine, 2022
BackgroundPrognostic models can help to identify patients at risk for end-stage kidney disease (ESKD) at an earlier stage to provide preventive medical interventions. Previous studies mostly applied the Cox proportional hazards model.
Xi Shi, Xi Shi, Tingyu Qu, Gijs Van Pottelbergh, Marjan van den Akker, Marjan van den Akker, Bart De Moor   +6 more
doaj   +1 more source

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

An approach to trial design and analysis in the era of non-proportional hazards of the treatment effect [PDF]

, 2014
Background: Most randomized controlled trials with a time-to-event outcome are designed and analysed under the proportional hazards assumption, with a target hazard ratio for the treatment effect in mind. However, the hazards may be non-proportional.
D Stark, DR Cox, FMS Barthel, FMS Barthel, KS Thomas, M Schemper, Mahesh KB Parmar, P Royston, P Royston, P Royston, Patrick Royston, PK Andersen, PM Grambsch, TS Mok, WP McGuire   +14 more
core   +2 more sources

Estimation in Cox proportional hazards model with heteroscedastic errors in covariates

Modern Stochastics: Theory and Applications
Consistent estimators of the baseline hazard rate and the regression parameter are constructed in the Cox proportional hazards model with heteroscedastic measurement errors, assuming that the baseline hazard function belongs to a certain class of ...
Oksana Chernova
doaj   +1 more source

Estimation of treatment effects in weighted log-rank tests

Contemporary Clinical Trials Communications, 2017
Non-proportional hazards have been observed in clinical trials. The log-rank test loses power and the standard Cox model generally produces biased estimates under such conditions.
Ray S. Lin, Larry F. León
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source