Results 41 to 50 of about 1,576,634 (357)

A New Approach to Proportional Hazards Modeling for Estimating Customer Lifetime Value [PDF]

arXiv, 2022
Estimating customer lifetime value (CLV or LTV) is extremely important for making better business decisions. The proposed flexible proportional hazards model allows an estimation of lifetime value in contractual settings. This approach takes advantage of a churn model, which is assumed to be available.
arxiv  

An Assessment of the Cox Proportional Hazards Regression Model for Epidemiologic Studies

Risk Analysis, 2018
The basic assumptions of the Cox proportional hazards regression model are rarely questioned. This study addresses whether hazard ratio, i.e., relative risk (RR), estimates using the Cox model are biased when these assumptions are violated.
S. Moolgavkar, E. T. Chang, Heather N. Watson, E. Lau   +3 more
semanticscholar   +1 more source

DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network [PDF]

BMC Medical Research Methodology, 2016
BackgroundMedical practitioners use survival models to explore and understand the relationships between patients’ covariates (e.g. clinical and genetic features) and the effectiveness of various treatment options. Standard survival models like the linear
Jared Katzman, Uri Shaham, A. Cloninger, Jonathan Bates, Tingting Jiang, Y. Kluger   +5 more
semanticscholar   +1 more source

Are non-constant rates and non-proportional treatment effects accounted for in the design and analysis of randomised controlled trials? A review of current practice

BMC Medical Research Methodology, 2019
Background Most clinical trials with time-to-event primary outcomes are designed assuming constant event rates and proportional hazards over time. Non-constant event rates and non-proportional hazards are seen increasingly frequently in trials.
Kim Jachno, Stephane Heritier, Rory Wolfe   +2 more
doaj   +1 more source

Analysis of the Proportional Hazards Model With Sparse Longitudinal Covariates

Journal of the American Statistical Association, 2015
Regression analysis of censored failure observations via the proportional hazards model permits time-varying covariates that are observed at death times.
Hongyuan Cao, M. Churpek, D. Zeng, J. Fine   +3 more
semanticscholar   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Fitting The First Birth Interval in Indonesia Using Weibull Proportional Hazards Model

Cauchy: Jurnal Matematika Murni dan Aplikasi, 2018
The first birth interval is one of the indicators of women’s fertility rate. Because in most cases the first birth interval contains censored observations, the only appropriate statistical method to handle such data is survival analysis.
Alfensi Faruk, Endro Setyo Cahyono, Ning Eliyati   +2 more
doaj   +1 more source

Statistical power to detect violation of the proportional hazards assumption when using the Cox regression model

Journal of Statistical Computation and Simulation, 2017
The use of the Cox proportional hazards regression model is wide-spread. A key assumption of the model is that of proportional hazards. Analysts frequently test the validity of this assumption using statistical significance testing.
P. Austin
semanticscholar   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Efficient Estimation and Inference in the Proportional Odds Model for Survival Data

Mathematics, 2022
In modeling time-to-event data with long-term survivors, the proportional hazards model is widely used for its easy and direct interpretation as well as the flexibility to accommodate the past information and allow time-varying predictors.
Xifen Huang, Chaosong Xiong, Tao Jiang, Junfeng Lu, Jinfeng Xu   +4 more
doaj   +1 more source