Results 101 to 110 of about 748,596 (376)
Effect of a Clinical Evidence Technology on Patient Skin Disease Outcomes in Primary Care: A Cluster-Randomized Controlled Trial [PDF]
, 2018 Objective: Providers’ use of clinical evidence technologies (CETs) improves their diagnosis and treatment decisions. Despite these benefits, few studies have evaluated the impact of CETs on patient outcomes. Investigators evaluated the effect of one CET,
Burke, Marianne +1 more
core +1 more source
Prognostic Analysis of IgA Nephropathy Patients with High Risk of CKD Progression Treated with Glucocorticoid: a Retrospective Study [PDF]
Zhongguo quanke yixueBackground IgA nephropathy (IgAN) is a common primary glomerulonephritis worldwide, and the improvement of glucocorticoid on the renal prognosis of IgAN patients with high risk of CKD progression remains unclear.
GAO Ge, ZHANG Xinyue, FENG Yuhua, DOU Jingyu, WU Xueying, CHENG Genyang
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
The Duration of Trade Revisited: Continuous-Time vs. Discrete-Time Hazards [PDF]
The recent literature on the duration of trade has predominantly analyzed the determinants of trade flow durations using Cox proportional hazards models.
Hess, Wolfgang, Persson, Maria
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Journal of Research in Medical Sciences, 2017 Background: Cox proportional hazard model is the most common method for analyzing the effects of several variables on survival time. However, under certain circumstances, parametric models give more precise estimates to analyze survival data than Cox ...
Sadegh Kargarian-Marvasti +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Linking period and cohort life-expectancy linear increases in Gompertz proportional hazards models [PDF]
In a Gompertz mortality model with constant yearly improvements at all ages, linear increases in period life expectancy correspond to linear increases in the respective cohort life expectancy.
Adam Lenart, Trifon I. Missov
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Estimating panel data duration models with censored data [PDF]
, 2005 This paper presents a method for estimating a class of panel data duration models, under which an unknown transformation of the duration variable is linearly related to the observed explanatory variables and the unobserved heterogeneity (or frailty ...
Lee, S.
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Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Goodness-of-fit tests for the frailty distribution in proportional hazards models with shared frailty. [PDF]
Frailty models account for the clustering present in grouped event time data. A proportional hazards model with shared frailties expresses the hazard for each subject. Often a one-parameter gamma distribution is assumed for the frailties. The choice of a
Claeskens, Gerda +2 more
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