Results 91 to 100 of about 1,130,957 (303)

Design Scheme and Proportional Analysis of the Kufic Inscription on the Stone Mihrab of Turan Posht Mosque and Pilgrimage Site, Yazd [PDF]

open access: yesپیکره
Introduction: The Mosque and Pilgrimage Site of Turan Posht has a stone mihrab currently preserved in the Freer Gallery of Art in the United States. This stone mihrab features inscriptions in Kufic and Thuluth scripts. Based on the date inscribed on this
Sahar Salehi   +3 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Proportions of the aesthetic African-Caribbean face: idealized ratios, comparison with the golden proportion and perceptions of attractiveness

open access: yesMaxillofacial Plastic and Reconstructive Surgery, 2018
Background In the absence of clear guidelines for facial aesthetic surgery, most surgeons rely on expert intuitive judgement when planning aesthetic and reconstructive surgery.
Angelos Mantelakis   +6 more
doaj   +1 more source

Structured proportional representation

open access: yesTheoretical Computer Science, 2017
Multi-winner voting rules aiming at proportional representation, such as those suggested by Chamberlin and Courant and by Monroe, partition an electorate into virtual districts, such that a representative is assigned to each district; these districts are formed based on the voters' preferences.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Golden proportions as predictors of attractiveness and malocclusion

open access: yesIndian Journal of Dental Research, 2014
Objective: In recent years, the golden proportions have been evaluated by various researchers in the general population and orthodontic patients to establish their correlation with facial attractiveness and esthetics, but with conflicting results.
Ahluwalia Rajiv, Yadav Juhi
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

INNOVATIVE CLOTHING DESIGN FOR WOMEN DURING PREGNANCY [PDF]

open access: yesAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2015
During pregnancy there is an evident change in the physical appearance of a woman's body. The most evident change is the substantial weight gain, increased abdominal region, torso and hip, and limbs thickening.
POPESCU Georgeta   +2 more
doaj  

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