Results 151 to 160 of about 111,297 (312)
ABSTRACT Drug‐induced liver injury remains a severe but underdiscussed adverse effect of nitrofurantoin. This case uniquely describes hepatic injury occurring after four doses of nitrofurantoin, with a disproportionate rise in AST and rapid complete recovery following discontinuation of the drug. A RUCAM score of six supports the probability of DILI.
Mahir H. Sampat
wiley +1 more source
The Development of a Novel Controlled Release Drug Delivery System
The aim of this research was to formulate, characterise and assess the feasibility of a novel drug delivery system known as the in situ gelling matrix (ISGM) where a hydrophilic polymer is suspended in a non-aqueous solvent that converts into a gel when ...
Babu, Kavitha Mary Vadakkel
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Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz +1 more
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Adrenergic neuron blocking properties of (±)-propranolol and (+)-propranolol
The action of (±)-propranolol and (+)-propranolol on the electrical stimulation of adrenergic nerves to smooth muscle has been studied in the isolated ear artery from rabbits and the isolated vas deferens preparation from rats.
A M Barrett, Barbara Nunn
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Radiographic remission of a presumptive unresectable haemangiosarcoma treated with toceranib, piroxicam, and propranolol. In a dog with ACVIM Stage B2 myxomatous mitral valve disease where doxorubicin‐based chemotherapy was contraindicated, this multimodal regimen achieved marked tumour reduction and radiographic disappearance.
Woo Dae Park
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Temporomandibular joint dislocation due to acute propranolol intoxication
Abbas Aghabiklooei1, Homan Elahi2, Babak Mostafazadeh31Department of Medical Toxicology and Forensic Medicine, Iran University of Medical Sciences, Tehran, Iran; 2Firouzgar Hospital, Department of ENT, Tehran, Iran; 3Department of Medical Toxicology and ...
Babak Mostafazadeh +5 more
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Objective:. Infantile hemangioma (IH) is a benign vascular tumor that occurs in 5% of infants, predominantly in female and preterm neonates. Propranolol is the mainstay of treatment for IH.
Annegret Holm +4 more
doaj +1 more source
Invitro skin penetration of propranolol enantiomers
Transfer rates of individual enantiomers of propranolol across human skin were determined in vitro. Percutaneous penetration of propranolol from propylene glycol was negligible at the concentration previously reported to show enantioselective transfer in
Watkinson, A. C. +3 more
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Crystallization of the drug propranolol with dicarboxylic acids yielded stable crystalline molecular salts with oxalic and fumaric acids in molar ratios of 1 : 1 and 2 : 1, and with maleic acid in a molar ratio of 1 : 1 only.
Beļakovs, Sergejs +4 more
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