Using a new high-throughput video-tracking platform to assess behavioural changes in Daphnia magna exposed to neuro-active drugs [PDF]
, 2019 © 2019. ElsevierOne of the major challenges that faces today regulatory risk assessment is to speed up the way of assessing threshold sublethal detrimental effects of existing and new chemical products.
Barata Martí, Carlos +8 more
core +1 more source
A randomized, controlled trial of oral propranolol in infantile hemangioma.
New England Journal of Medicine, 2015 BACKGROUND Oral propranolol has been used to treat complicated infantile hemangiomas, although data from randomized, controlled trials to inform its use are limited.
C. Léauté-Labrèze +47 more
semanticscholar +1 more source
Propranolol exhibits activity against hemangiomas independent of beta blockade
npj Precision Oncology, 2019 Propranolol is a widely used beta blocker that consists of a racemic mixture of R and S stereoisomers. Only the S stereoisomer has significant activity against the beta-adrenergic receptor.
Maiko Sasaki +11 more
semanticscholar +1 more source
Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. [PDF]
, 2005 BACKGROUND: Nonselective beta-adrenergic blockers decrease portal pressure and prevent variceal hemorrhage. Their effectiveness in preventing varices is unknown.
Bosch, J +12 more
core +1 more source
The effect of Midazolam and Propranolol on fear memory reconsolidation in ethanol-withdrawn rats: Influence of D-cycloserine [PDF]
, 2014 Background: Withdrawal from chronic ethanol facilitates the formation of contextual fear memory and delays the onset to extinction, with its retrieval promoting an increase in ethanol consumption.
Espejo, Pablo Javier +4 more
core +1 more source
Propranolol for the treatment of anxiety disorders: Systematic review and meta-analysis
Journal of Psychopharmacology, 2016 The effects of propranolol in the treatment of anxiety disorders have not been systematically evaluated previously. The aim was to conduct a systematic review and meta-analysis of randomised controlled trials, addressing the efficacy of oral propranolol ...
Serge A. Steenen +5 more
semanticscholar +1 more source
Involvement of propranolol in suicides: cross-sectional study using coroner-reported data
BJPsych OpenBackground Propranolol is a beta-blocker medication indicated mostly for heart rhythm conditions and for physical symptoms of anxiety. Prescriptions for propranolol in the UK have increased since 2008.
Hayley C. Gorton +4 more
doaj +1 more source
Cardio-Protection Afforded by Β-Blockade Is Maintained During Resistance Exercise [PDF]
, 2017 Objectives Whether or not the cardio-protective effect of β-adrenergic blockade is retained during resistance exercise has not been systematically evaluated.
Conviser, Jason M. +3 more
core +2 more sources
British Journal of Pharmacology, EarlyView., 2023 Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
wiley +1 more source
Toxics, 2022 Severe hyper-catecholaminergic states likely cause heart failure and cardiac fibrosis. While previous studies demonstrated the effects of beta-blockade in experimental models of single-catecholamine excess states, the detailed benefits of beta-blockade ...
Cheng-Ken Tsai +6 more
doaj +1 more source