Results 31 to 40 of about 42,221 (227)

Trigeminovascular effects of propranolol in men and women, role for sex steroids

Annals of Clinical and Translational Neurology, 2022
Objective Assess whether propranolol modulates the trigeminovascular system in both men and women. Methods We investigated the effect of propranolol (80 mg, 90 min after oral administration, corresponding to Tmax) on the increase in dermal blood flow of ...
Eloísa Rubio‐Beltrán, Rianne M. Schoon, Jeffrey van denBerg, Catharina C. M. Schuiling‐Veninga, Birgit C. P. Koch, Carlos M. Villalón, Jorie Versmissen, A. H. Jan Danser, Anton H. van denMeiracker, Khatera Ibrahimi, Antoinette MaassenVanDenBrink   +10 more
doaj   +1 more source

Propranolol in hypertension [PDF]

Postgraduate Medical Journal, 1968
Summary Twenty-four hypertensive patients, eleven of whom had angina pectoris as well, have been treated with propranolol in doses up to 400 mg daily. The thirteen patients without angina received methyldopa 2 g daily in addition to propranolol. A significant reduction of systolic and diastolic blood pressure was found in both groups.
S N, Tewari, R H, Grant
openaire   +2 more sources

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Propranolol in Treatment of Huge and Complicated Infantile Hemangiomas in Egyptian Children

Dermatology Research and Practice, 2014
Background. Infantile hemangiomas (IHs) are the most common benign tumours of infancy. Propranolol has recently been reported to be a highly effective treatment for IHs.
Basheir A. Hassan, Khalid S. Shreef
doaj   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Perbandingan Efektivitas dan Keamanan Ligasi dengan atau Tanpa Propranolol pada Anak dengan Hipertensi Portal

Sari Pediatri
Latar belakang. Hipertensi portal (HP) didefinisikan sebagai peningkatan tekanan portal >5 mmHg, jika >12 mmHg dapat terjadi perdarahan saluran cerna.
Kadim Muzal, Amrina Rasyada
doaj   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

The impact of propranolol on nitric oxide and total antioxidant capacity in patients with resistant hypertension—evidence from the APPROPRIATE trial

BMC Research Notes, 2020
Objectives The objective was to assess the effect of propranolol on oxidative stress and anti-oxidant potential in patients with resistant hypertension as a secondary analysis of the APPROPRIATE trial.
H. N. Ranasinghe, N. Fernando, S. Handunnetti, P. N. Weeratunga, P. Katulanda, S. Rajapakse, P. Galappatthy, G. R. Constantine   +7 more
doaj   +1 more source

Melatonin Levels in 89 Individuals With Smith Magenis Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley   +1 more source

Terazosin and propranolol as blockers to the deleterious effect of nicotine in a random skin flap, in the rat Terazosina e propanolol como bloqueadores do efeito deletério da nicotina em um retalho cutâneo randômico, no rato

Acta Cirúrgica Brasileira, 2004
PURPOSE: To evaluate the effect of Terazosin and Propranolol on the prevention of necrosis induced by nicotine, in a random skin flap. METHODS: This study utilized 32 adult male Wistar-EPM rats divided, at random, into four groups of eight animals each ...
Andre V. Fonseca, Lydia Masako Ferreira, Heitor C. Gomes, Sandro Percário   +3 more
doaj   +1 more source