Results 11 to 20 of about 41,520 (219)

Efficacy of Combined Topical Timolol and Oral Propranolol for Treating Infantile Hemangioma: A Meta-Analysis of Randomized Controlled Trials

Frontiers in Pharmacology, 2020
BackgroundOral propranolol has become the first-line treatment for infantile hemangioma (IH). However, combined therapy with topical timolol and oral propranolol has been proposed as a more effective IH treatment strategy.
Junbo Qiao, Junjie Lin, Dexin Zhang, Junhua Li, Changkuan Chen, Hongye Yu, Xiaodi Li, Bin Fang   +7 more
doaj   +1 more source

Refractive Outcome in Preterm Newborns With ROP After Propranolol Treatment. A Retrospective Observational Cohort Study

Frontiers in Pediatrics, 2019
Background: Recent explorative studies suggest that propranolol reduces retinopathy of prematurity (ROP) progression, but the short-term effects of propranolol treatment at 1 year of corrected age have not been extensively evaluated.Methods: A multi ...
Luca Filippi, Giacomo Cavallaro, Lavinia Perciasepe, Elena Sandini, Gabriella Araimo, Giulia Regiroli, Giulia Regiroli, Genny Raffaeli, Paola Bagnoli, Massimo Dal Monte, Maura Calvani, Pina Fortunato, Silvia Osnaghi, Salvatore De Masi, Fabio Mosca, Fabio Mosca   +15 more
doaj   +1 more source

Combinative effects of β-elemene and propranolol on the proliferation, migration, and angiogenesis of hemangioma [PDF]

PeerJ, 2023
Hemangioma (HA) is one of the most common benign vascular tumors among children. Propranolol is used as the first-line treatment for hemangioma and is a non-selective blocker of the β-adrenergic receptor.
Zhenyu Wang, Yinxian Chen, Lin Yang, Dunbiao Yao, Yang Shen   +4 more
doaj   +2 more sources

The effect of propranolol on the prognosis of hepatocellular carcinoma: A nationwide population-based study.

PLoS ONE, 2019
BackgroundBeta-blockers can reduce recurrence, metastasis, and mortality in various cancers. In this study, we investigated the effect of propranolol, a non-selective beta-blocker on overall survival (OS) in unresectable/metastatic hepatocellular ...
Ping-Ying Chang, Chi-Hsiang Chung, Wei-Chou Chang, Chun-Shu Lin, Hsuan-Hwai Lin, Ming-Shen Dai, Ching-Liang Ho, Wu-Chien Chien   +7 more
doaj   +1 more source

Splanchnic Venous Compression Enhances the Effects of ß‐Blockade in the Treatment of Postural Tachycardia Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Splanchnic venous pooling induced by upright posture triggers a compensatory increase in heart rate (HR), a response that is exaggerated in patients with postural tachycardia syndrome.
Emily C. Smith, André Diedrich, Satish R. Raj, Alfredo Gamboa, Cyndya A. Shibao, Bonnie K. Black, Amanda Peltier, Sachin Y. Paranjape, Italo Biaggioni, Luis E. Okamoto   +9 more
doaj   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Japanese Clinical Practice Guidelines for Vascular Tumors, Vascular Malformations, Lymphatic Malformations, and Lymphangiomatosis 2022. [PDF]

J Plast Reconstr Surg
ABSTRACT The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety, and systematizing treatment, employing evidence‐based medicine techniques and aimed at improvement of the outcomes.
Kinoshita Y, Ishikawa K, Akita S, Koh K, Sasaki S, Jinnin M, Mimura H, Osuga K, Ozeki M, Nagahama M, Fujino A, Aoki Y, Asai A, Aramaki-Hattori N, Ishiura R, Inoue M, Iwashina Y, Ohshiro T, Ogawa K, Ozaki M, Ochi J, Onozawa S, Kato M, Kaneko T, Kawakami T, Kitagawa A, Kurita M, Kuwano Y, Kono T, Seike S, Takagi S, Takakura N, Tachibana T, Tanoue S, Chuman K, Nakaoka H, Nakamura Y, Nagai F, Niimi Y, Nosaka S, Nozaki T, Nomura T, Hashimoto K, Hayashi A, Hirakawa S, Hirabayashi T, Furukawa T, Furukawa H, Hori Y, Maekawa T, Matsuoka K, Mori H, Morii E, Morimoto A, Moriwaki Y, Yuzuriha S, Rikihisa N, Fujita M, Yamahana Y, Deie K, Tozawa A, Hasegawa D, Higashiyama A, Maeda D, Asayama S, Arai Y, Iwata Y, Uka M, Usui H, Uchiyama M, Endo S, Endo H, Ono R, Oshima N, Otsuka T, Ohara K, Kagami S, Kakihara T, Kato M, Kanamori H, Kamata M, Kawaguchi A, Kishi A, Kitagawa H, Kim K, Kobayashi T, Saito T, Shikano Y, Shimada S, Suzuki K, Takahashi M, Takami S, Takeda R, Tanaka A, Tanaka K, Tamura S, Tamura M, Danno K, Tsuboi K, Nakajima Y, Nakatani R, Noguchi M, Nozawa A, Hashizume N, Hayakawa M, Hayashi D, Fukumoto T, Honda M, Matsuda N, Maruguchi H, Murakami N, Yaguchi K, Yasue S, Yoshihara H, Yoshimatsu R, Yamamoto K, Wada S.   +116 more
europepmc   +3 more sources

Low-Dose Propranolol Prevents Functional Decline in Catecholamine-Induced Acute Heart Failure in Rats

Toxics, 2022
Severe hyper-catecholaminergic states likely cause heart failure and cardiac fibrosis. While previous studies demonstrated the effects of beta-blockade in experimental models of single-catecholamine excess states, the detailed benefits of beta-blockade ...
Cheng-Ken Tsai, Bo-Hau Chen, Hsin-Hung Chen, Rebecca Jen-Ling Hsieh, Jui-Chen Lee, Yi-Ting Chu, Wen-Hsien Lu   +6 more
doaj   +1 more source

Efficacy and safety assessment of propranolol tablets vs. oral solution for infantile hemangioma: a retrospective study in China

Frontiers in Pediatrics
BackgroundPropranolol for infantile hemangiomas (IHs) is effective and relatively safe. However, propranolol has different formulations and there is no consensus on the optimal formulation for IHs.
Wenting Chen, Hua Qian, Qi Sun, Shan Zhang, Lei Zhu, Yafen Wu, Yingying Qian, Bingbing Wang, Wei Li   +8 more
doaj   +1 more source

Involvement of propranolol in suicides: cross-sectional study using coroner-reported data

BJPsych Open
Background Propranolol is a beta-blocker medication indicated mostly for heart rhythm conditions and for physical symptoms of anxiety. Prescriptions for propranolol in the UK have increased since 2008.
Hayley C. Gorton, Charlotte Archer, Thikra Algahtani, Faraz Mughal, Caroline S. Copeland   +4 more
doaj   +1 more source