Results 41 to 50 of about 42,221 (227)

Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure. [PDF]

PLoS ONE, 2013
OBJECTIVE: Only a limited proportion of patients needing pharmacological control of portal hypertension are hemodynamic responders to propranolol.
Mercedes Reboredo, Haisul C Y Chang, Roberto Barbero, Carlos M Rodríguez-Ortigosa, Francisco Pérez-Vizcaíno, Asunción Morán, Mónica García, Jesús M Banales, Norberto Carreño, Félix Alegre, Ignacio Herrero, Jorge Quiroga, Jesús Prieto, Bruno Sangro   +13 more
doaj   +1 more source

Optimal dosing for vascular anomalies paediatric patients with population pharmacokinetic model of sirolimus

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Sirolimus is currently used off‐label for paediatric patients with vascular anomalies. However, the optimal dosage regimen for paediatric patients remains controversial. This study aimed to determine the optimal dosing regimen of sirolimus in these patients using a population pharmacokinetic (PK) model.
Seongmee Jeong, Jungryul Kim, Woojin Jung, Jiyeon Jeon, Hyeongjun Jo, Kyoung‐Bin Ryu, Ja‐Young Hong, Kwan Soo Kim, Seongjun Yang, Hee Young Ju, Hwi‐yeol Yun, Jung‐woo Chae, Keon Hee Yoo, Soyoung Lee   +13 more
wiley   +1 more source

Involution of a Large Parotid Hemangioma with Oral Propranolol: An Illustrative Report and Review of the Literature

Case Reports in Pediatrics, 2012
Propranolol has emerged as a new treatment option for infantile hemangiomas. We describe a 20-month-old boy with a large right parotid hemangioma diagnosed at the age of 37 days.
Elpis Mantadakis, Emmanouela Tsouvala, Savas Deftereos, Vassilios Danielides, Athanassios Chatzimichael   +4 more
doaj   +1 more source

Propranolol: A 50-year historical perspective

Annals of Indian Academy of Neurology, 2019
Propranolol is a beta-adrenergic receptor antagonist that was developed by the British scientist Sir James Black primarily for the treatment of angina pectoris, more than 50 years ago.
A V Srinivasan
doaj   +1 more source

Clinical Significance of Screening Electrocardiograms for the Administration of Propranolol for Problematic Infantile Hemangiomas

International Journal of Pediatrics, 2021
Objective. Low-dose nonselective β blockade is an effective treatment for problematic infantile hemangioma (PIH). Screening electrocardiograms (ECG) are performed prior to the initiation of propranolol to minimize the risk of exacerbating undiagnosed ...
James D. Phillips, Tyler Merrill, J. Reed Gardner, R. Thomas Collins, Jenika Sanchez, Adam B. Johnson, Brian K. Eble, Larry D. Hartzell, Jay M. Kincannon, Gresham T. Richter   +9 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

ELECTROPHORESIS, EarlyView.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source

The anti-cancer effect of Propranolol in K562 cell line: an in vitro study

Armaghane Danesh Bimonthly Journal, 2016
Introduction: Β-AR receptors are one of the proteins involved in cancer and stress. The therapeutic activity of β-blockers such as propranolol is attributed to the blockade of β1-adrenergic receptors (ARs).
S Bastani, M Mohamadzade, Y Pazhang
doaj  

Propranolol 0.2% Eye Micro-Drops for Retinopathy of Prematurity: A Prospective Phase IIB Study

Frontiers in Pediatrics, 2019
Background: Oral propranolol reduces retinopathy of prematurity (ROP) progression, although not safely. Propranolol 0.1% eye micro-drops administered to newborns with stage 2 ROP are well-tolerated, but not sufficiently effective.Methods: A multi-center ...
Luca Filippi, Giacomo Cavallaro, Giacomo Cavallaro, Elettra Berti, Letizia Padrini, Gabriella Araimo, Giulia Regiroli, Giulia Regiroli, Genny Raffaeli, Genny Raffaeli, Valentina Bozzetti, Paolo Tagliabue, Barbara Tomasini, Annalisa Mori, Giuseppe Buonocore, Massimo Agosti, Angela Bossi, Gaetano Chirico, Salvatore Aversa, Pina Fortunato, Silvia Osnaghi, Barbara Cavallotti, Martina Suzani, Maurizio Vanni, Giulia Borsari, Simone Donati, Giuseppe Nascimbeni, Daniel Nardo, Stefano Piermarocchi, Giancarlo la Marca, Giulia Forni, Silvano Milani, Ivan Cortinovis, Maura Calvani, Paola Bagnoli, Massimo Dal Monte, Anna Maria Calvani, Alessandra Pugi, Eduardo Villamor, Gianpaolo Donzelli, Fabio Mosca, Fabio Mosca   +41 more
doaj   +1 more source

High‐Throughput Multi‐Capillary Electrophoresis

ELECTROPHORESIS, EarlyView.
Multi‐capillary electrophoresis enables high‐throughput pharmaceutical analysis through simultaneous multi‐capillary operation, achieving a five‐fold reduction in run time per sample with improved sensitivity and linearity. Method transfer from single‐capillary systems is straightforward, supporting rapid and accurate quantification across diverse ...
Jana Drewes, Sarah Meyer, Isobel Roberts, Cleo Fanny, Philip A. Doble, Dayanne Mozaner Bordin, Janice I. McCauley   +6 more
wiley   +1 more source