Results 51 to 60 of about 28,589 (204)
Abstract Purpose Patients with severe ocular motility restriction and/or large angle strabismus due to Graves' orbitopathy (GO) cannot be adequately addressed with conventional strabismus surgery using large muscle recessions. Muscle tendon elongation surgery, using a spacer of bovine pericardium (Tutopatch®) has emerged as a valuable alternative.
H. M. Jellema +7 more
wiley +1 more source
Proptosis, a rare presentation of acute myeloid leukemia − AML M6 in a child
Acute myeloid leukemia (AML) M6 or acute erythroid leukemia is an extremely rare type of AML accounting for 3–4% of all AML cases. In children, AML is even rarer, in accordance to the fact that only 0.5–4.6% of all cancer-affected individuals are ...
Ragalikhith Kesamneni +3 more
doaj +1 more source
Exploring tear fluid biomarkers and the ocular surface in thyroid eye disease
Abstract Purpose To examine ocular surface changes and inflammatory tear fluid biomarkers in patients with thyroid eye disease (TED). Methods We included 106 Graves' disease (GD) patients (36 without TED, 32 with active and 38 with inactive TED) and 106 age‐ and sex‐matched healthy subjects for ophthalmological evaluation, including ocular surface ...
Mikael Thomassen Neset +13 more
wiley +1 more source
A Rare Cause of Proptosis in Childhood: Langerhans Cell Histiocytosis
A three-year-old male patient was admitted to the clinic with proptosis in his right eye. He had a history of fever with an unknown etiology. In examination, right proptosis was observed and an immobile mass was palpated at the lateral wall of the right ...
Mustafa Vatansever +4 more
doaj +1 more source
ABSTRACT Crouzon and Apert syndromes are rare syndromic craniosynostoses frequently associated with craniofacial and dental anomalies, including tooth agenesis. Although individual studies have reported tooth agenesis prevalence data in specific populations, no attempts have been made to systematically synthesise these data.
M. Cecilia Becerril Santos +3 more
wiley +1 more source
Malignant melanoma of the rectum presenting as orbital metastasis
An orbital mass being the presenting sign of disseminated systemic metastasis is a rare clinical picture. Here, the authors describe the case of a 52-year old Asian-Indian female who presented with unilateral proptosis and motility restriction.
Natasha Narayanan +4 more
doaj +1 more source
Bilateral proptosis: an unusual primary presentation of scurvy—a case report [PDF]
S. Damini +3 more
openalex +1 more source
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source
The detection of secreted biomarkers enables molecular variations monitoring of organoid status. In this study, the non‐destructive quantification for the whole‐course growth and drug‐response of PDOs is first realized using a multifunctional microfluidic chip‐based system(ASMO) that integrates culturing, drug incubation, and biomarker detection ...
Yu Zhang +12 more
wiley +1 more source
Caroticocavernous Fistulae: Clinical Presentation, Imaging, and Endovascular Treatment
Caroticocavernous fistulas (CCFs) occur due to an abnormal communication between the high-pressure carotid artery system and the relatively lower pressure cavernous sinus system.
Pushpinder S. Khera +8 more
doaj +1 more source

