Results 151 to 160 of about 8,955 (198)

Correlation between depressive-like behavior and gut microbiota in mice with hypothyroidism. [PDF]

open access: yesWorld J Psychiatry
Guo HJ   +7 more
europepmc   +1 more source

The Pharmacokinetics of Propylthiouracil

Acta Pharmacologica Et Toxicologica, 1974
The half‐life of propylthiouracil was determined in 7 normal subjects after intravenous injection of 400 mg of the drug. An average value of 77 ± 17 minutes (mean ± S. D.) was found. As the concentration of the drug in the blood declined by a rapid phase followed by a more slow phase a two‐compartment model was used for further calculations, and the ...
L Skovsted
exaly   +3 more sources

Fulminant hepatic failure associated with propylthiouracil: A case report with treatment emphasis on the use of plasmapheresis

open access: yesJournal of Clinical Apheresis, 2005
Propylthiouracil is a commonly used medication for hyperthyroidism. Though propylthiouracil-induced hepatotoxicity is a rarely encountered problem, death due to fulminant hepatic failure may occur.
Yücel Ustundag   +2 more
exaly   +2 more sources

Propylthiouracil-Induced Antineutrophil Cytoplasmic Antibody-Associated Vasculitis after COVID-19 Vaccination

open access: yesVaccines, 2021
We report the case of a patient who developed antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) after receiving the coronavirus disease 2019 (COVID-19) vaccine BNT162b (Pfizer–BioNTech).
Yasuaki Hirooka   +2 more
exaly   +2 more sources

The propylthiouracil dilemma

Current Opinion in Endocrinology, Diabetes & Obesity, 2012
To bring to the attention of healthcare professionals the additional information on propylthiouracil (PTU)-related hepatotoxicity, based on a reanalysis of medical files reported to the Food and Drug Administration (1982-2008) for acute liver failure in PTU-treated hyperthyroid patients, and propose recommendations for the clinical use of PTU. Thirteen
Glinoer, Daniel, Cooper, David
openaire   +3 more sources

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