Spectrophotometric Determination of Methimazole by Silicomolybdenum Blue
Under optimum reaction conditions, Ammonium silicomolybdate could be quantitatively reduced to silicomolybdenum blue by hydrosulfuryl(-SH) in methimazole molecule, and the content of methimazole was determinated indirectly through determinating the ...
Wen Xinrong, Tu Changqing
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From antithyroid therapy to oral necrosis: oral manifestations of methimazole-induced agranulocytosis: a case report [PDF]
Background Methimazole is a widely used antithyroid medication with a well-documented risk of hematological adverse effects, particularly agranulocytosis.
Haitham Medhioub +5 more
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Methimazole-Induced Pleural Effusion in the Setting of Graves’ Disease
Methimazole is a thionamide drug that inhibits the synthesis of thyroid hormones by blocking the oxidation of iodine in the thyroid gland. We report a case of methimazole-induced recurrent pleural effusion.
Le Yu Khine +5 more
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The Role of Endoplasmic Reticulum Stress in Cell Injury Induced by Methimazole on Pancreatic Cells [PDF]
Purpose: Methimazole is an anti-thyroid agent, especially as main therapy option for Graves’ disease in children and adults. Drug induced pancreatitis is one of the known adverse effect of methimazole mentioned in case reports.
Özge Yazıcı +3 more
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Effects of methimazole on the elimination of irinotecan [PDF]
To study the possible pharmacokinetic and pharmacodynamic interactions between irinotecan and methimazole.A patient treated for colorectal cancer with single agent irinotecan received methimazole co-medication for Graves' disease. Irinotecan pharmacokinetics and side effects were followed during a total of four courses (two courses with and two courses
van der Bol, J.M. +9 more
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Antineutrophilic Cytoplasmic Antibody Positive Vasculitis Associated with Methimazole Use
ANCA-associated vasculitis (AAV) is a rare and potentially life threatening complication associated with antithyroid drug use. It is more commonly reported with propylthiouracil, with fewer cases reported with methimazole use. We present the case of a 55-
Deep Shikha +3 more
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Methimazole Associated Neutropenia in a Preterm Neonate Treated for Hyperthyroidism [PDF]
Maternal Graves’ disease is relatively uncommon with an estimated incidence of 0.4%–1% of all pregnancies, but only 1–5% of newborns delivered to mothers with Graves’ disease develop overt clinical signs and symptoms of hyperthyroidism. Here, we describe
Dimitrios Angelis +2 more
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Drug cross-reactivity between methimazole and propylthiouracil causing recurrent pancreatitis in thyroid storm [PDF]
Drug-induced pancreatitis represents 1.1% of acute pancreatitis cases. To date, eight cases of antithyroid drug (ATD)-induced pancreatitis have been reported, including seven associated with methimazole (MMI) and one with carbimazole; however, no cases ...
Yuriko Yamazaki +8 more
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A case of severe erythema nodosum induced by methimazole
Erythema nodosum (EN), is the most common variant of septal panniculitis and is possibly a delayed hypersensitivity reaction triggered by a wide range of antigenic stimuli.
Selma Emre +4 more
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