Results 11 to 20 of about 7,915 (181)

Morphological changes in liver of methimazole treated rats, a pilot study

Journal of University Medical & Dental College, 2021
BACKGROUND & OBJECTIVE: Thyrotoxicosis is a disease in which thyroid hormones are raised, and we have seen multiple patients suffering from this ailment in Pakistan. Methimazole is an anti-thyroid drug for thyrotoxicosis.
Maira Bhatti, Waqas Iqbal Butt, Shahnaz Fatima, Fouzia Perveen, Sabeen Arjumand, Amna Iqbal Butt   +5 more
doaj   +1 more source

Protective Effect of Natural Antioxidant Compounds on Methimazole Induced Oxidative Stress in a Feline Kidney Epithelial Cell Line (CRFK)

Veterinary Sciences, 2021
The treatment of choice for feline hyperthyroidism is the administration of the antithyroid drug methimazole. Both the endocrinopathy and the drug adverse reactions (e.g., hepatotoxicosis, gastrointestinal disorders, and renal injury) are partly due to ...
Flavia Girolami, Alessia Candellone, Watanya Jarriyawattanachaikul, Giorgia Meineri, Carlo Nebbia, Paola Badino   +5 more
doaj   +1 more source

The Potential Prebiotic Berberine Combined With Methimazole Improved the Therapeutic Effect of Graves’ Disease Patients Through Regulating the Intestinal Microbiome

Frontiers in Immunology, 2022
Graves’ disease, a typical metabolism disorder, causes diffuse goiter accompanied by ocular abnormalities and ocular dysfunction. Although methimazole (MI) is a commonly used drug for the treatment of GD, the efficacy of methimazole is only limited to ...
Zhe Han, Chaoping Cen, Qianying Ou, Yonggui Pan, Jiachao Zhang, Jiachao Zhang, Dongxue Huo, Dongxue Huo, Kaining Chen   +8 more
doaj   +1 more source

Spectrophotometric Determination of Methimazole by Silicomolybdenum Blue

E3S Web of Conferences, 2018
Under optimum reaction conditions, Ammonium silicomolybdate could be quantitatively reduced to silicomolybdenum blue by hydrosulfuryl(-SH) in methimazole molecule, and the content of methimazole was determinated indirectly through determinating the ...
Wen Xinrong, Tu Changqing
doaj   +1 more source

A rare combination of congenital anomalies following in utero methimazole exposure

Journal of Pediatric Surgery Case Reports, 2021
The use of methimazole for the treatment of hyperthyroidism in the first trimester of pregnancy has been linked to several congenital malformations. Most commonly reported is choanal atresia; however, other anomalies have been described including aplasia
Taylor Shaw, Alexis Brantley, Hannah Cockrell, Colin Muncie, Barry Berch   +4 more
doaj   +1 more source

Methimazole-Induced Aplastic Anemia with Concomitant Hepatitis in a Young Filipina with Graves’ Disease

Journal of the ASEAN Federation of Endocrine Societies, 2019
A 34-year-old Filipino with Graves’ disease on methimazole came in due to fever, sore throat and jaundice. Patient was initially diagnosed with methimazole induced agranulocytosis and drug induced liver injury.
Natalia Wijaya, Celeste Ong-Ramos
doaj   +1 more source

Efficacy of methimazole before the administration of radioactive iodine in the management of Graves’ disease: a systematic review and meta-analysis

São Paulo Medical Journal, 2023
BACKGROUND: The efficacy of anti-thyroid drugs in conjunction with radioactive iodine therapy in the management of Graves’ disease is still controversial.
Ikeoluwapo Kendra Bolakale-Rufai, Imodoye Abioro, Samuel Osobuchi Ngene, Yohannes Woldeamanuel   +3 more
doaj   +1 more source

The efficacy of a unique topical dose of methimazole in cats – A case presentation

Medicamentul Veterinar, 2022
Methimazole or thiamazole is the most commonly used remedy in the medical management of hyperthyroidism, an endocrine disorder with growing prevalence, particularly in geriatric feline patients. Unfortunately, veterinarians have little, or most often, no
Andreea Pap, Crina L. Mosneang, Eugenia Dumitrescu, Muselin Florin, Doma O. Alexandru, Cristina T. Romeo   +5 more
doaj  

Assessment of bone marrow-derived mesenchymal stem cells capacity for odontogenic differentiation and dentin regeneration in methimazole-treated albino rats (Light microscopic Study)

Saudi Dental Journal, 2022
Background: Methimazole is an antithyroid drug. It has side effects on many tissues. Bone marrow-derived mesenchymal stem cells (BM-MSCs) are promising in the field of tissue regeneration.
Amany A. Rabea
doaj   +1 more source

Methimazole-Induced Pleural Effusion in the Setting of Graves’ Disease

Case Reports in Endocrinology, 2019
Methimazole is a thionamide drug that inhibits the synthesis of thyroid hormones by blocking the oxidation of iodine in the thyroid gland. We report a case of methimazole-induced recurrent pleural effusion.
Le Yu Khine, Dong Won Kim, Omolola Olajide, Chelsey White, Yousef Shweihat, Henry Driscoll   +5 more
doaj   +1 more source