Results 41 to 50 of about 10,913 (208)
Nitrile Functionalized Methimazole-Based Ionic Liquids
, 2010 The alkylation reaction of 2-mercapto-1-methylimidazole 1b with 2-chloroacetonitrile and 2-chloropropionitrile produced S-alkyl methimazole chlorides 2a and 2b which were subjected to anion metathesis with lithium bis(trifluoromethanesulfonyl)amide ...
Siriwardana, Amal I. +15 more
core +2 more sources
Hypoglycemic Coma Caused by Methimazole-Induced Insulin Autoimmune Syndrome, a Case Study
, 2023 Yinhui He, Aihua Xu, Danqing Yu, Suzhen Lv, Haiyan Xu Department of Endocrinology, Lishui Municipal Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang Province, 323000, People’s Republic of ChinaCorrespondence:
He Y, Xu A, Lv S, Yu D, Xu H
core
Rheumatology &Autoimmunity, EarlyView.A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa +3 more
wiley +1 more source
Methimazole-Based Ionic Liquids
, 2016 The alkylation reaction of 2-mercapto-1-methylimidazole 1a with iodoethane and chlorobutane produced S-alkylmethimazole halides 2a and 2b which were subjected to anion metathesis with two different metal salts (MA) to afford methimazole-based room ...
Glen B. Deacon (1463308) +7 more
core +1 more source
Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability
The Journal of Physiology, EarlyView.Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi +12 more
wiley +1 more source
Mitigation of Methimazole-Induced Hepatic Injury by Taurine in Mice
, 2014 Methimazole is the most widely prescribed antithyroid medication in humans. However, hepatotoxicity is a deleterious adverse effect associated with methimazole administration. No specific protective agent has been developed against this complication yet.
Reza HEIDARI +3 more
core +1 more source
Frontiers in Immunology, 2023 A complex network of interactions exists between the olfactory, immune and central nervous systems. In this work we intend to investigate this connection through the use of an immunostimulatory odorant like menthol, analyzing its impact on the immune ...
Noelia Casares +12 more
doaj +1 more source
The Determination and Pharmacokinetics of Methimazole in Biological Fluids [PDF]
, 1988 The Determination and Pharmacokinetics of Methimazole in Biological Fluids. The development of methimazole therapy, its mechanism of action and pharmacokinetics in man have been briefly reviewed.
Donnelly, Mary Clare
core +4 more sources
Methimazole protection of rats against gentamicin-induced nephrotoxicity
, 1994 Methimazole was previously shown to protect rats, mice, and (or) dogs against cisplatin-, cephaloridine-, 2-bromohydro-quinone-, and S-(1,2-dichlorovinyl)-L-cysteine-induced nephrotoxicity.
Todd M. O'Hara +4 more
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Chemistry of Spontaneous Alkylation of Methimazole with 1,2-Dichloroethane
Molecules, 2021 Spontaneous S-alkylation of methimazole (1) with 1,2-dichloroethane (DCE) into 1,2-bis[(1-methyl-1H-imidazole-2-yl)thio]ethane (2), that we have described recently, opened the question about its formation pathway(s).
Leo Štefan +5 more
doaj +1 more source