Results 61 to 70 of about 9,775 (218)
Hepatoprotective Effect of Acetylated Amino Acid on Methimazole Induced Hepatotoxicity in Mice
Objective: To explore the hepatoprotective effect of N‐acetylcysteine on methimazole induced hepatic damage in mice. Study Design: Randomized control trial.
Zunera Hakim , Akbar Waheed , Aroosa Ishtiaq , Wardha Mazhar
doaj
Hypothyroidism is one of the most common pathological conditions in modern clinical practice. Due to the fact that the targets of thyroid hormones are virtually all organs and tissues, the morphological and clinical manifestations arising with a ...
Aleksey M. Chaulin +3 more
doaj +1 more source
ABSTRACT Aim Reduced placental mTOR signaling is associated with intrauterine growth restriction and impaired maternal and placental metabolism. Since maternal hypothyroidism induces intrauterine growth restriction, and maternal treatment with kisspeptin‐10 (Kp10) has been shown to improve feto‐placental development in hypothyroid rats, this study ...
Bianca Reis Santos +9 more
wiley +1 more source
Mitigation of Methimazole-Induced Hepatic Injury by Taurine in Mice
Methimazole is the most widely prescribed antithyroid medication in humans. However, hepatotoxicity is a deleterious adverse effect associated with methimazole administration. No specific protective agent has been developed against this complication yet.
Reza HEIDARI +3 more
core +1 more source
ABSTRACT Thyroid hormones (THs) are under negative feedback regulation via the hypothalamic–pituitary‐thyroid (HPT) axis. How this axis operates to keep the circulating THs within a narrow physiological range is not well understood quantitatively. Led by the design principle of robust homeostatic feedback control, here we review and synthesize the ...
Li Jing, Sarahna A. Moyd, Qiang Zhang
wiley +1 more source
Methimazole induced lichenoid eruptions: an unusual case
This is a case report of a 31-year-old male presented to the Endocrinology outpatient department of our hospital with hyperthyroidism and was prescribed tablet methimazole 30mg once daily and tablet propranolol 40mg once daily.
G. N., Vibhashree +5 more
core +1 more source
Objective Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) and sodium‐glucose cotransporter 2 inhibitors (SGLT2i) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear.
Derin Karacabeyli +4 more
wiley +1 more source
Here in this paper, we report a 31-year-old case admitted with symptoms of hyperthyroidism that was then diagnosed with Grave's disease (GD) and underwent treatments with a low dosage of methimazole (10 mg/day).
Aminorroaya, Ashraf +2 more
core +1 more source
Amitriptyline Induced Life‐Threatening Steven–Johnson Syndrome: Case Report
ABSTRACT Stevens–Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine, and carbamazepine are commonly implicated.
Wondwosen Mengist Dereje +3 more
wiley +1 more source
Acute Drug-Induced Cholestatic Syndrome in Basedow Graves’ Disease
Introduction: Graves’ disease (GD), an autoimmune disorder caused by high levels of auto-antibodies against the thyroid-stimulating hormone receptor, is considered the most common cause of thyrotoxicosis, characterized by features such as goiter ...
Tiucă Robert Aurelian +3 more
doaj +1 more source

