Results 61 to 70 of about 15,768 (275)
Characterization of iodothyronine sulfotransferase activity in rat liver [PDF]
, 1997 Sulfation is an important pathway in the metabolism of thyroid hormone because it strongly facilitates the degradation of the hormone by the type I iodothyronine deiodinase.
Greef, W.J. de +4 more
core +2 more sources
Acta Physiologica, Volume 242, Issue 4, April 2026.ABSTRACT Thyroid hormones (THs) are under negative feedback regulation via the hypothalamic–pituitary‐thyroid (HPT) axis. How this axis operates to keep the circulating THs within a narrow physiological range is not well understood quantitatively. Led by the design principle of robust homeostatic feedback control, here we review and synthesize the ...
Li Jing, Sarahna A. Moyd, Qiang Zhang
wiley +1 more source
Methimazole-Related Substances: Structural Characterization and In Silico Toxicity Assessment
CrystalsThe continuous tightening of pharmaceutical regulations forces drug manufacturers to unambiguously characterize the substances related to the active pharmaceutical ingredients (API). Here, we report the synthesis, complete spectroscopic, chromatographic,
Leo Štefan +4 more
doaj +1 more source
Cytometric evaluation of intracellular IFN-γ and IL-4 levels in thyroid follicular cells from patients with autoimmune thyroid diseases [PDF]
, 2011 Background In recent few years is underlined that altered balance of pro- and anti-inflammatory cytokines play an important role in the pathogenesis of AITD.
Artur Bossowski +5 more
core +1 more source
Arthritis &Rheumatology, Volume 78, Issue 3, Page 654-664, March 2026.Objective Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) and sodium‐glucose cotransporter 2 inhibitors (SGLT2i) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear.
Derin Karacabeyli +4 more
wiley +1 more source
Russian Open Medical Journal, 2021 Hypothyroidism is one of the most common pathological conditions in modern clinical practice. Due to the fact that the targets of thyroid hormones are virtually all organs and tissues, the morphological and clinical manifestations arising with a ...
Aleksey M. Chaulin +3 more
doaj +1 more source
Amitriptyline Induced Life‐Threatening Steven–Johnson Syndrome: Case Report
Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT Stevens–Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine, and carbamazepine are commonly implicated.
Wondwosen Mengist Dereje +3 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT Amiodarone therapy may induce thyroid dysfunction in approximately 20% of patients, either amiodarone‐induced hypothyroidism (AIH) or thyrotoxicosis (AIT). Both situations may occur at any time during treatment or even months to years after drug withdrawal due to tissue storage with slow systemic release.
Daniela M. Soares, Lia Ferreira
wiley +1 more source
Effects of thyroid status and thyrostatic drugs on hepatic glucuronidation of lodothyronines and other substrates in rats - Induction of phenol UDP-glucuronyltransferase by methimazole [PDF]
, 1995 Glucuronidation of iodothyronines in rat liver is catalyzed by at least three UDP-glucuronyltransferases (UGTs): bilirubin UGT, phenol UGT, and androsterone UGT.
Bonthuis, F. (Fred) +6 more
core +2 more sources
Beyond the Norm: Atypical Manifestations of Aspergillosis
Respirology Case Reports, Volume 14, Issue 3, March 2026.We describe a rare case of Aspergillus infection presenting as a chest mass, underscoring the diagnostic challenges of fungal diseases in immunocompromised patients and highlighting the importance of considering unusual manifestations in clinical practice.
Leila Zahiri +5 more
wiley +1 more source