Results 81 to 90 of about 15,768 (275)

New cases of δ‐aminolevulinic acid dehydratase deficiency: Functional insights into gene variants using an innovative mouse liver model

Journal of Internal Medicine, Volume 299, Issue 1, Page 126-142, January 2026.
Abstract Background Dysfunction of δ‐aminolevulinic acid dehydratase (ALAD), the second enzyme involved in heme biosynthesis, leads to two pathologies: genetic and acquired. The genetic form is an ultrarare, severe childhood‐onset disease inherited in an autosomal recessive manner, whereas the acquired form usually affects adults due to enzyme ...
Elena Di Pierro, Isabel Solares, Daniel Jericó, Francisco J. Castelbón, Javier Tomás Solera, Antoni Riera‐Mestre, María Barreda‐Sánchez, Carlo Poci, Annamaria Nicolli, Francesco Urigo, Ana Sampedro, Rafael Enríquez de Salamanca, Matteo Marcacci, Matías A. Ávila, Pauline Harper, Marta G. Fanlo‐Maresma, Encarna Guillén‐Navarro, Giovanna Graziadei, Andrea Wenzel, Bodo B. Beck, Paolo Ventura, Montserrat Morales‐Conejo, Antonio Fontanellas   +22 more
wiley   +1 more source

Mutação E449X no receptor β do hormônio tireoidiano associada com doença tireoidiana auto-imune e retardo neuropscicomotor grave [PDF]

, 2008
OBJECTIVE: To report the clinical and molecular aspects of a patient with a diagnosis of Resistance to Thyroid Hormone (RTH) harboring the E449X mutation associated with autoimmune thyroid disease and severe neuropsychomotor retardation.
GURGEL, Maria Helane Costa, LIMA, Grayce Ellen da C. Paiva, MACIEL, Lea Maria Zanini, MAGALHAES, Rejane Araujo, MAGALHÃES, Patricia Kunzle Ribeiro, MONTENEGRO JUNIOR, Renan M., MONTENEGRO, Renan Magalhães   +6 more
core   +2 more sources

Epidemiology and Clinical Outcomes of HTLV‐1: A Comprehensive Narrative Review of Endemic and Nonendemic Regions

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Human T‐lymphotropic virus Type 1 (HTLV‐1) is a globally distributed, oncogenic retrovirus endemic in specific regions, including southwestern Japan, sub‐Saharan Africa, the Caribbean, parts of South America (notably Brazil), Iran, and Indigenous communities in Australia. Although most infections are asymptomatic, a minority of carriers develop severe,
Bezhan Noori, Ramin Shahbahrami, Yousef Douzandegan, Sayed-Hamidreza Mozhgani, Mehdi Norouzi, Seyed Mohammad Jazayeri, Arif Ansori   +6 more
wiley   +1 more source

Crystal structure of a methimazole-based ionic liquid

Acta Crystallographica Section E: Crystallographic Communications, 2015
The structure of 1-methyl-2-(prop-2-en-1-ylsulfanyl)-1H-imidazol-3-ium bromide, C7H11N2S+·Br−, has monoclinic (P21/c) symmetry. In the crystal, the components are linked by N—H...Br and C—H...Br hydrogen bonds. The crystal structure of the title compound
Jamie C. Gaitor, Manuel Sanchez Zayas, Darrel J. Myrthil, Frankie White, Jeffrey M. Hendrich, Richard E. Sykora, Richard A. O'Brien, John T. Reilly, Arsalan Mirjafari   +8 more
doaj   +1 more source

Prognostic value of thyrotropin receptor antibodies (TRAb) in Graves' disease: a 120 months prospective study [PDF]

, 2007
In most trials, at least 30-60% of patients with Graves' disease treated with antithyroid drugs relapse within 2 years after therapy withdrawal. At present, there are no prognostic parameters available early in treatment to indicate patients likely to ...
AGABITI ROSEI E, AGOSTI B, CAPPELLI C, CASTELLANO M, DE MARTINO E, DELBARBA A, GANDOSSI E, PIROLA I, PIZZOCARO C   +8 more
core   +1 more source

Thyroid Storm in a Hypothyroid Patient: A Case Report of Concurrent Graves′ Disease and Hashimoto′s Thyroiditis

Case Reports in Critical Care, Volume 2026, Issue 1, 2026.
Thyroid storm, a life‐threatening endocrine emergency, is exceptionally rare in patients with hypothyroidism. This case highlights the unique challenge of diagnosing and managing thyroid storm in the context of concurrent Graves′ disease and Hashimoto′s thyroiditis, a paradoxical coexistence of autoimmune thyroid disorders.
Katrina Villegas, Rouba Isshak, Mubarak Yusuf, Mourad Ismail, Konstantinos Leou, Lipi Buch   +5 more
wiley   +1 more source

Immunosuppressive treatment for immune thrombocytopenia which masked Graves′ disease

Journal of Family Medicine and Primary Care, 2015
A 71-year-old female patient followed primary immune thrombocytopenia (ITP) was admitted to endocrinology unit with excessive sweating. We started methimazole for Graves′ disease.
Suleyman Baldane, Suleyman Hilmi Ipekci, Levent Kebapcilar   +2 more
doaj   +1 more source

Thyroid Storm at Sea: A Case Report of Algae‐Induced Thyrotoxicosis

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Iodine‐induced thyrotoxicosis (IIT), also known as the Jod‐Basedow phenomenon, is a rare yet recognized cause of hyperthyroidism. While iodinated contrast is the most frequent trigger, iodine‐rich supplements such as seaweed products or supplements can also precipitate thyrotoxicosis, particularly in individuals with prior chronic iodine deficiency or ...
Alynna Knaub, Amanda Cecchini, John Janousek, Laura Strojny, Jairo Noreña, Zachary Pawlikowski, Kalyani Sen   +6 more
wiley   +1 more source

Endocrine‐Taste Crosstalk: A Scoping Review on Thyroid Dysfunction and Its Genetic Links to Taste Receptors With Dysgeusia

International Journal of Endocrinology, Volume 2026, Issue 1, 2026.
Thyroid disorders are a common endocrine condition globally, affecting various bodily systems and metabolism. Changes in thyroid function affect smell and taste; yet, many patients remain unaware of their dysosmia and dysgeusia. Currently, there is a lack of detailed information regarding changes in physiological taste thresholds across different taste
Panchami Pai, Ananya Chadaga, Srikant Natarajan, Chetana Chandrashekar, Gabriel Rodrigues, Sunitha Carnelio, Suraiya Saleem   +6 more
wiley   +1 more source

Early Low‐Dose Rituximab for Mild‐to‐Moderate Thyroid Eye Disease: A Preliminary Evaluation of Efficacy and Safety

International Journal of Endocrinology, Volume 2026, Issue 1, 2026.
Background Thyroid eye disease (TED) is an autoimmune inflammatory condition linked to thyroid dysfunction, which can result in disfigurement and potential vision loss. Recently, immunomodulatory therapies such as rituximab have demonstrated potential benefit in managing TED.
Ming Lu, Luqiang Wang, Xuelian Zhang, Suraiya Saleem   +3 more
wiley   +1 more source