Results 51 to 60 of about 9,775 (218)

Methimazole-induced reproductive endocrine system disruption and hepatotoxicity: insights from a Trichogaster trichopterus animal model

BMC Pharmacology and Toxicology
Background Methimazole is commonly prescribed for managing hyperthyroidism, although concerns regarding its reproductive and hepatic adverse effects persist. This study aimed to evaluate the dose-dependent effects of methimazole on reproductive endocrine
Mahdi Ahmadinia, Tahereh Naji, Homayoun Hosseinzadeh Sahafi   +2 more
doaj   +1 more source

Pharmacotherapy of hyperthyroidism in cats (ro.) [PDF]

Medicamentul Veterinar, 2013
Currently, the feline hyperthyroidism possesses three types of treatment that includes medication, surgery and radioactive therapie. The success of these therapies consists in obtaining favorable results, by inhibiting thyroid hormone secretion, reducing
Andreea Pap, Romeo T. Cristina
doaj  

Pre-treatment Neutropenia in Children and Adolescents with Autoimmune Hyperthyroidism

JCRPE, 2021
Objective:Neutropenia can occur in untreated autoimmune hyperthyroidism (AIH) or in association with treatment with the anti-thyroid drug, methimazole (MMI).
Melissa Kaori S. Litao, Ana Gutierrez Alvarez, Bina Shah   +2 more
doaj   +1 more source

Acute Intermittent Porphyria Triggered by COVID‐19 Mimicking Guillain–Barré Syndrome: A Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Acute intermittent porphyria (AIP) is a rare heme biosynthesis disorder in which the accumulation of neurotoxic porphyrin precursors precipitates neurovisceral attacks. Intercurrent infections, including coronavirus disease 2019 (COVID‐19), may trigger or exacerbate AIP and complicate diagnosis, as clinical manifestations can resemble those of
Payman Sadeghi, Masood Ghahvechi Akbari, Seyed Abbas Hassani, Hosein Alimadadi, Morteza Heidari, Vahid Ziaee   +5 more
wiley   +1 more source

Multifocal Benign Metastasizing Pleomorphic Adenoma Presenting as a Lymphoma: An Atypical Clinical Picture Demystified by an Unusual PLAG1 Gene Rearrangement Detected on RNA Next Generation Sequencing

Diagnostic Cytopathology, Volume 54, Issue 5, Page E140-E145, May 2026.
ABSTRACT A 57‐year‐old female presented to urgent care with exertional dyspnea, back pain, and several months of night sweats. Imaging showed an anterior mediastinal mass with concurrent hepatic and vertebral lesions, raising suspicion for a hematolymphoid malignancy.
Poorva Singh, Spencer M. Erickson, Kathryn Baxstrom, Paari Murugan   +3 more
wiley   +1 more source

Facile synthesis of carbon quantum dot/silver nanocomposite and its application for colorimetric detection of methimazole

, 2017
Here we present a very simple and fast method for preparation of carbon quantum dot/silver (CQD/Ag) nanocomposites at room temperature. Glucose-derived CQDs were prepared by a facile microwave-assisted method and used as both reducing and stabilizing ...
Asadollahi, Hamideh, Hallaj, Tooba, Song, Zhenlun, de Frutos, Marta, Hildebrandt, Niko, Frutos, Marta,, Amjadi, Mohammad, Frutos, Marta, De   +7 more
core   +1 more source

Substrate for Thyroid Hormone Synthesis: Biochemistry, Evolution, and Physiology

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Two proposed sequence of events for thyroxine formation in patients expressing mutant thyroglobulin. (A) (1) TSH stimulation drives expression of misfolded TG. (2) Unremitting ER stress. (3) Stress‐induced cell death. (4) Dead thyrocytes release their contents. (5) The contents become iodinated. (6) Forming thyroxine.
Crystal Young, Peter Arvan
wiley   +1 more source

Methimazole-Related Substances: Structural Characterization and In Silico Toxicity Assessment

Crystals
The continuous tightening of pharmaceutical regulations forces drug manufacturers to unambiguously characterize the substances related to the active pharmaceutical ingredients (API). Here, we report the synthesis, complete spectroscopic, chromatographic,
Leo Štefan, Ivica Đilović, Lara Saftić Martinović, Robert Vianello, Ana Čikoš   +4 more
doaj   +1 more source

Multisystem Sarcoidosis Presenting With Hypercalcemia, Lytic Bone Lesion, and Mesenteric Panniculitis in Chronic Kidney Disease

Clinical Case Reports, Volume 14, Issue 4, April 2026.
The clinical photograph shows bilateral leg swelling with right‐sided predominance and cutaneous changes. CT images (A–C) demonstrate abdominal and retroperitoneal lymphadenopathy, and image D shows a hypodense lytic spinal lesion, suggesting multifocal disease involving the abdomen, retroperitoneum, and spine.
Aishwarya Holi, Karuna Rayamajhi, Satya Rijal, Niket Shah, Aaron Sousa, Gina Chacon Osorio   +5 more
wiley   +1 more source

METHIMAZOLE EMBRYOPATHY. DELINEATION OF THE PHENOTYPE

, 1997
We report on a further case of congenital anomalies in a child exposed to methimazole during the first trimester of pregnancy (from first to seventh gestational week), and define a specific malformation pattern related to prenatal methimazole exposure ...
CLEMENTI, MAURIZIO, MAMMI I, DI GIANANTONIO E, TENCONI R., PELO E   +4 more
core   +1 more source