Results 31 to 40 of about 7,915 (181)

Chemistry of Spontaneous Alkylation of Methimazole with 1,2-Dichloroethane

Molecules, 2021
Spontaneous S-alkylation of methimazole (1) with 1,2-dichloroethane (DCE) into 1,2-bis[(1-methyl-1H-imidazole-2-yl)thio]ethane (2), that we have described recently, opened the question about its formation pathway(s).
Leo Štefan, Ana Čikoš, Robert Vianello, Ivica Đilović, Dubravka Matković-Čalogović, Miljenko Dumić   +5 more
doaj   +1 more source

Autoimmune Disease Risk With GLP‐1RA, DPP‐4i, and SGLT2i Treatment in Patients With Diabetes

ACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Objective Dipeptidyl peptidase‐4 inhibitors (DPP‐4i), glucagon‐like peptide‐1 receptor agonists (GLP‐1RA), and sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are widely used for type 2 diabetes, yet their comparative immunologic safety is uncertain.
Arjun Mahajan, David W. Bates, Alessandro Doria, Dinah Foer, Avery H. LaChance, Jeffrey A. Sparks   +5 more
wiley   +1 more source

Antineutrophilic Cytoplasmic Antibody Positive Vasculitis Associated with Methimazole Use

Case Reports in Endocrinology, 2015
ANCA-associated vasculitis (AAV) is a rare and potentially life threatening complication associated with antithyroid drug use. It is more commonly reported with propylthiouracil, with fewer cases reported with methimazole use. We present the case of a 55-
Deep Shikha, Jonathan Harris, Christine Resta, Patricia Park   +3 more
doaj   +1 more source

Methimazole-Induced ANCA Vasculitis: A Case Report

Diagnostics, 2021
Rapidly progressive glomerulonephritis (RPGN) is a syndrome which presents rapid loss of renal function. Vasculitis represents one of the major causes, often related to anti-neutrophil cytoplasmic antibodies (ANCA).
Precil Diego Miranda de Menezes Neves, Lucas Braga Mota, Cristiane Bitencourt Dias, Luis Yu, Viktoria Woronik, Lívia Barreira Cavalcante, Denise Maria Avancini Costa Malheiros, Lectícia Barbosa Jorge   +7 more
doaj   +1 more source

Graves' Disease Presenting as Refractory Panic Attacks: Diagnostic Clarification Through Thyroid Scintigraphy

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Graves' disease may rarely present with predominant neuropsychiatric symptoms, such as severe, treatment‐resistant panic attacks, leading to misdiagnosis as a primary psychiatric disorder. We describe a 30‐year‐old woman with refractory panic attacks and night terrors who was initially treated with anxiolytics and antidepressants.
Mahsa Satari Gholami
wiley   +1 more source

Methimazole-induced reproductive endocrine system disruption and hepatotoxicity: insights from a Trichogaster trichopterus animal model

BMC Pharmacology and Toxicology
Background Methimazole is commonly prescribed for managing hyperthyroidism, although concerns regarding its reproductive and hepatic adverse effects persist. This study aimed to evaluate the dose-dependent effects of methimazole on reproductive endocrine
Mahdi Ahmadinia, Tahereh Naji, Homayoun Hosseinzadeh Sahafi   +2 more
doaj   +1 more source

Feline diabetes. Part 2: monitoring and management with other diseases

In Practice, Volume 48, Issue 5, Page 228-241, June 2026.
Background: Diabetes mellitus (DM) in cats is commonly seen in primary care practice and presents several clinical and practical challenges to owners and vets. In recent years feline DM has seen paradigm shifts in management and monitoring. Aim of the article: In this second article of a series on feline DM, we look at the monitoring options that are ...
Ian Ramsey, Anna Kraemer
wiley   +1 more source

Methimazole-Related Substances: Structural Characterization and In Silico Toxicity Assessment

Crystals
The continuous tightening of pharmaceutical regulations forces drug manufacturers to unambiguously characterize the substances related to the active pharmaceutical ingredients (API). Here, we report the synthesis, complete spectroscopic, chromatographic,
Leo Štefan, Ivica Đilović, Lara Saftić Martinović, Robert Vianello, Ana Čikoš   +4 more
doaj   +1 more source

Weaning stress induced alterations to the hypothalamic‐pituitary‐thyroid and ‐adrenal axes in swine

Physiological Reports, Volume 14, Issue 12, June 2026.
Abstract Combined modulation of the hypothalamic–pituitary–thyroid (HPT) and hypothalamic–pituitary–adrenal (HPA) axes is known to play a critical role in maintaining physiological stability in response to stress. In this study, stress induced modulation of these axes was examined using 20 pigs/treatment either weaned (WN), weaned with feed/water ...
Isabel B. Walpole, Alyssa A. Smith, Kaylyn G. Rudy, Dayeon Jeon, J. Scott Radcliffe, J. Alex Pasternak   +5 more
wiley   +1 more source

Probing the Biological Plausibility of Fluoride as an Endocrine Disruptor

Birth Defects Research, Volume 118, Issue 5, May 2026.
ABSTRACT Background Fluoride has come under recent scrutiny regarding concerns over potential neurodevelopmental and endocrine‐related toxicities, with recent reviews by the National Toxicology Program (NTP) and European Food Safety Authority (EFSA) concluding with moderate or reasonable confidence, respectively, that exposure to drinking water having ...
Ashley M. Mudd, Bladimir J. Ovando, George P. Daston   +2 more
wiley   +1 more source