Results 31 to 40 of about 10,913 (208)

Effects of methimazole on the elimination of irinotecan [PDF]

, 2011
PURPOSE: To study the possible pharmacokinetic and pharmacodynamic interactions between irinotecan and methimazole. METHODS: A patient treated for colorectal cancer with single agent irinotecan received methimazole co-medication for Graves' disease ...
Visser, Theo, Bol, Jessica, de Jong, FA (Floris), Planting, AST, Wiemer, Erik, Mathijssen, RHJ; id_orcid, Wiemer, Erik; id_orcid, Verweij, Jaap, Loos, Walter, Mathijssen, RHJ, Schellens, JH, van Aken, MO   +11 more
core   +4 more sources

Scalable Process of Methimazole

, 2022
Base hydrolysis of imidazole carboxylate was observed to be an efficient route for the scalable synthesis of the antithyroid drug methimazole. Ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate (12) was produced as a key intermediate in the ...
Naresh Kumar Katari (14266453), Ramesh Goura (14266447), Pradeep Rebelly (14266459), Ramprasad Achampeta Kodanda (14266456), Surendra Babu Manubolu Surya (14266450)   +4 more
core   +1 more source

Zinc(II)-methimazole complexes: synthesis and reactivity [PDF]

, 2015
The tetrahedral S-coordinated complex [Zn(MeImHS)(4)](ClO4)(2), synthesised from the reaction of [Zn(ClO4)(2)] with methimazole (1-methyl-3H-imidazole-2-thione, MeImHS), reacts with triethylamine to yield the homoleptic complex [Zn(MeImS)(2)] (MeImS ...
LIPPOLIS, VITO, C. Caltagirone, BETTOSCHI, ALEXANDRE, M. C. Aragoni, T. Pivetta, Castellano C, E. Valletta, M. Arca, ARAGONI, MARIA CARLA, F. Demartin, F. Isaia, PIVETTA, TIZIANA, V. Lippolis, ISAIA, FRANCESCO, Demartin F, ARCA, MASSIMILIANO, A. Bettoschi, C. Castellano, CALTAGIRONE, CLAUDIA, Valletta E.   +19 more
core   +1 more source

Assessment of bone marrow-derived mesenchymal stem cells capacity for odontogenic differentiation and dentin regeneration in methimazole-treated albino rats (Light microscopic Study)

Saudi Dental Journal, 2022
Background: Methimazole is an antithyroid drug. It has side effects on many tissues. Bone marrow-derived mesenchymal stem cells (BM-MSCs) are promising in the field of tissue regeneration.
Amany A. Rabea
doaj   +1 more source

Summary of molecular docking positions for methimazole.

, 2020
Summary of molecular docking positions for methimazole.
Andrew R. Jones (2217223), Kerry A. Ramsbottom (8415615), Daniel F. Carr (6882968), Daniel J. Rigden (30029)   +3 more
core   +1 more source

Evaluation of Antioxidant Supplementation on Redox Unbalance in Hyperthyroid Cats Treated with Methimazole: A Blinded Randomized Controlled Trial

Antioxidants, 2019
Methimazole (MMI) is often the selected medical treatment for feline hyperthyroidism. However, the onset of MMI-related side effects (MMI-SE) is likely caused by oxidative stress.
Alessia Candellone, Paola Badino, Paola Gianella, Flavia Girolami, Graziella Raviri, Vittorio Saettone, Giorgia Meineri   +6 more
doaj   +1 more source

Methimazole Inhibits the Expression of GFAP and the Migration of Astrocyte in Scratched Wound Model In Vitro

Mediators of Inflammation, 2020
Astrocytes respond to central nervous system (CNS) insults with varieties of changes, such as cellular hypertrophy, migration, proliferation, scar formation, and upregulation of glial fibrillary acidic protein (GFAP) expression.
Lina Zhao, Xianyu Zhang, Chunhai Zhang
doaj   +1 more source

Photodissociation of Methimazole

, 2018
Results from photodissociation studies on methimazole for the paper "Photofragment Translational Spectroscopy Studies of H Atom Loss Following Ultraviolet Photoexcitation of Methimazole in the Gas ...
Cooper, Graham, Ashfold, Michael, Karsili, Tolga, Hansen, Christopher   +3 more
core   +1 more source

Changes in liver function, fluctuations in blood glucose, insulin secretion and gender differences in patients with hyperthyroidism after treatment with propranolol hydrochloride tablets coalition with methimazole tablets

Pakistan Journal of Pharmaceutical Sciences
To investigate liver function changes, blood glucose fluctuation, insulin secretion, and gender differences in hyperthyroidism patients before and after propranolol with methimazole.
Jianying Hu, Jiajia Dong, Weihong Huang, Yongxin Lin, Jianming Hong, Mingyong Cai   +5 more
doaj   +1 more source

Experimental modeling of hypothyroidism: principles, methods, several advanced research directions in cardiology

Russian Open Medical Journal, 2021
Hypothyroidism is one of the most common pathological conditions in modern clinical practice. Due to the fact that the targets of thyroid hormones are virtually all organs and tissues, the morphological and clinical manifestations arising with a ...
Aleksey M. Chaulin, Julia V. Grigorieva, Galina N. Suvorova, Dmitry V. Duplyakov   +3 more
doaj   +1 more source