Temporal impact of hypothyroidism on porcine fetal growth and skeletal development. [PDF]
Physiol RepAbstract In the fetal pig, circulating thyroid hormone and growth rate increase throughout gestation; however, the functional association between these coincident factors has not been established. We used a nonpathogenic model of induced fetal hypothyroidism, wherein pregnant gilts were treated with methimazole (MMI) for 21 days, starting on gestation ...
Rudy K +6 more
europepmc +2 more sources
Psychotic depression associated with Graves' disease: A case report on treatment prioritization. [PDF]
PCN RepAbstract Background Graves' disease can be accompanied by psychiatric symptoms, including affective and psychotic manifestations. When a well‐defined psychiatric syndrome occurs concurrently with a medical illness, determining whether it is directly attributable to the medical condition or represents an independent psychiatric disorder precipitated by ...
Kocha A +7 more
europepmc +2 more sources
Finger Allergic Contact Dermatitis by Proxy Induced by Feline Thiamazole Cream. [PDF]
Contact DermatitisContact Dermatitis, Volume 95, Issue 5, Page 517-518, November 2026.
Blanchard G +4 more
europepmc +2 more sources
Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine [PDF]
Advanced Pharmaceutical Bulletin, 2014 Purpose: Methimazole is the most convenient drug used in the management of hyperthyroid patients. However, associated with its clinical use is hepatotoxicity as a life threatening adverse effect.
Reza Heidari +3 more
doaj +1 more source
Cytoprotective Effects of Organosulfur Compounds against Methimazole-Induced Toxicity in Isolated Rat Hepatocytes [PDF]
Advanced Pharmaceutical Bulletin, 2013 Purpose: Methimazole is a drug widely used in hyperthyroidism. However, life-threatening hepatotoxicity has been associated with its clinical use. No protective agent has been found to be effective against methimazole-induced hepatotoxicity yet.
Mohammad Ali Eghba +2 more
doaj +1 more source
Metabolite Changes during the Transition from Hyperthyroidism to Euthyroidism in Patients with Graves’ Disease [PDF]
Endocrinology and Metabolism, 2022 Background An excess of thyroid hormones in Graves’ disease (GD) has profound effects on systemic energy metabolism that are currently partially understood.
Ho Yeop Lee +9 more
doaj +1 more source
Zagazig University Medical Journal, 2018 Kidney and thyroid functions interact with each other. Drugs used in treatment of any of them could have side reactions on any other organ. The effects of antithyroid medications on extrathyroidal organs could be due to oxidative stress and to damage in ...
Mohey Hulail +3 more
doaj +1 more source
Colorimetric Determination of Thioamide Drugs Based on the Surface Plasmon Resonance Band of Colloidal Silver Nanoparticles [PDF]
شیمی کاربردی روز, 2013 In this article, we report a new method for the determination of two thioamide drugs, propylthiouracil (PTU) and methimazole (MMZ), with unmodified silver nanoparticles (AgNPs).
Jafar Abolhasani +3 more
doaj +1 more source
Frontiers in Endocrinology, 2021 BackgroundHyperthyroidism is related to vascular atherosclerosis. Propylthiouracil (PTU) and methimazole, other than their antithyroid effects, may have different mechanisms in preventing atherogenesis in Graves’ disease.ObjectiveThis study aimed to ...
Wismandari Wisnu +9 more
doaj +1 more source