Results 21 to 30 of about 15,768 (275)
Thyroid dysfunction alters gut microbiota composition and alveolar bone levels in female mice. [PDF]
Abstract Thyroid hormone dysfunction has been implicated in both bone metabolism and gut microbial composition, yet the interplay between thyroid status, gut microbiota, and alveolar bone homeostasis remains unclear. In this study, female C57BL/6J mice were treated with triiodothyronine (T3) and thyroxine (T4) to induce hyperthyroidism or with ...
Thompson L, Coulter B, VanPutte C.
europepmc +2 more sources
Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]
Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher +3 more
core +1 more source
Analysis of Compounded Pharmaceutical Products to Teach the Importance of Quality in an Applied Pharmaceutics Laboratory Course [PDF]
Objective. To assess the effectiveness of a product-analysis laboratory exercise in teaching students the importance of quality in pharmaceutical compounding. Design.
Almoazen +9 more
core +2 more sources
Graves’ disease, a typical metabolism disorder, causes diffuse goiter accompanied by ocular abnormalities and ocular dysfunction. Although methimazole (MI) is a commonly used drug for the treatment of GD, the efficacy of methimazole is only limited to ...
Zhe Han +8 more
doaj +1 more source
A rare combination of congenital anomalies following in utero methimazole exposure
The use of methimazole for the treatment of hyperthyroidism in the first trimester of pregnancy has been linked to several congenital malformations. Most commonly reported is choanal atresia; however, other anomalies have been described including aplasia
Taylor Shaw +4 more
doaj +1 more source
Cytoprotective effects of melatonin against amitriptyline-induced toxicity in isolated rat hepatocytes [PDF]
Purpose: Amitriptyline, one of the commonly used tricyclic antidepressants, caused rare but severe hepatotoxicity in patients who received it continuously. Previous findings showed that the intermediate metabolites of amitriptyline produced by CYP450 are
Dastmalchi, S. +3 more
core +1 more source
Spectrophotometric Determination of Methimazole by Silicomolybdenum Blue
Under optimum reaction conditions, Ammonium silicomolybdate could be quantitatively reduced to silicomolybdenum blue by hydrosulfuryl(-SH) in methimazole molecule, and the content of methimazole was determinated indirectly through determinating the ...
Wen Xinrong, Tu Changqing
doaj +1 more source
BACKGROUND: The efficacy of anti-thyroid drugs in conjunction with radioactive iodine therapy in the management of Graves’ disease is still controversial.
Ikeoluwapo Kendra Bolakale-Rufai +3 more
doaj +1 more source
Flavin-containing monooxygenases: mutations, disease and drug response [PDF]
NOTICE: this is the author’s version of a work that was accepted for publication in Trends in Pharmacological Sciences. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality ...
Phillips, IR, Shephard, EA
core +1 more source
A 34-year-old Filipino with Graves’ disease on methimazole came in due to fever, sore throat and jaundice. Patient was initially diagnosed with methimazole induced agranulocytosis and drug induced liver injury.
Natalia Wijaya, Celeste Ong-Ramos
doaj +1 more source

