Results 21 to 30 of about 9,775 (218)

Protective Effect of Natural Antioxidant Compounds on Methimazole Induced Oxidative Stress in a Feline Kidney Epithelial Cell Line (CRFK)

open access: yesVeterinary Sciences, 2021
The treatment of choice for feline hyperthyroidism is the administration of the antithyroid drug methimazole. Both the endocrinopathy and the drug adverse reactions (e.g., hepatotoxicosis, gastrointestinal disorders, and renal injury) are partly due to ...
Flavia Girolami   +5 more
doaj   +1 more source

Aplasia Cutis Congenita Associated with the Use of Antithyroid Medications during Pregnancy: A Case Report [PDF]

open access: yesIranian Journal of Neonatology, 2022
Background: Aplasia Cutis Congenita (ACC) is a rare malformation characterized by localized congenital absence of the skin which was first described by Cordon in 1767. ACC is estimated to occur in approximately 1 to 3 cases in 10000 live births.
Pham Chi Kong, Huynh Nhat, Le Chi
doaj   +1 more source

Effects of Thymoquinone on Hypothalamic NPY and AgRP Gene Expression in Intact and Hypothyroidism- Model Rats [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2022
Background & Objective: Thymoquinone is the most important compound of Nigella sativa, which stimulates the activity of thyroid axis in healthy individuals and people with hypothyroidism.
Nasrin Ghahremani, Fariba Mahmoudi
doaj  

Morphological changes in liver of methimazole treated rats, a pilot study

open access: yesJournal of University Medical & Dental College, 2021
BACKGROUND & OBJECTIVE: Thyrotoxicosis is a disease in which thyroid hormones are raised, and we have seen multiple patients suffering from this ailment in Pakistan. Methimazole is an anti-thyroid drug for thyrotoxicosis.
Maira Bhatti   +5 more
doaj   +1 more source

The Potential Prebiotic Berberine Combined With Methimazole Improved the Therapeutic Effect of Graves’ Disease Patients Through Regulating the Intestinal Microbiome

open access: yesFrontiers in Immunology, 2022
Graves’ disease, a typical metabolism disorder, causes diffuse goiter accompanied by ocular abnormalities and ocular dysfunction. Although methimazole (MI) is a commonly used drug for the treatment of GD, the efficacy of methimazole is only limited to ...
Zhe Han   +8 more
doaj   +1 more source

Scalable Process of Methimazole

open access: yes, 2022
Base hydrolysis of imidazole carboxylate was observed to be an efficient route for the scalable synthesis of the antithyroid drug methimazole. Ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate (12) was produced as a key intermediate in the ...
Naresh Kumar Katari (14266453)   +4 more
core   +1 more source

Zinc(II)-methimazole complexes: synthesis and reactivity [PDF]

open access: yes, 2015
The tetrahedral S-coordinated complex [Zn(MeImHS)(4)](ClO4)(2), synthesised from the reaction of [Zn(ClO4)(2)] with methimazole (1-methyl-3H-imidazole-2-thione, MeImHS), reacts with triethylamine to yield the homoleptic complex [Zn(MeImS)(2)] (MeImS ...
LIPPOLIS, VITO   +19 more
core   +1 more source

A rare combination of congenital anomalies following in utero methimazole exposure

open access: yesJournal of Pediatric Surgery Case Reports, 2021
The use of methimazole for the treatment of hyperthyroidism in the first trimester of pregnancy has been linked to several congenital malformations. Most commonly reported is choanal atresia; however, other anomalies have been described including aplasia
Taylor Shaw   +4 more
doaj   +1 more source

Efficacy of methimazole before the administration of radioactive iodine in the management of Graves’ disease: a systematic review and meta-analysis

open access: yesSão Paulo Medical Journal, 2023
BACKGROUND: The efficacy of anti-thyroid drugs in conjunction with radioactive iodine therapy in the management of Graves’ disease is still controversial.
Ikeoluwapo Kendra Bolakale-Rufai   +3 more
doaj   +1 more source

The efficacy of a unique topical dose of methimazole in cats – A case presentation

open access: yesMedicamentul Veterinar, 2022
Methimazole or thiamazole is the most commonly used remedy in the medical management of hyperthyroidism, an endocrine disorder with growing prevalence, particularly in geriatric feline patients. Unfortunately, veterinarians have little, or most often, no
Andreea Pap   +5 more
doaj  

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