Results 21 to 30 of about 9,775 (218)
The treatment of choice for feline hyperthyroidism is the administration of the antithyroid drug methimazole. Both the endocrinopathy and the drug adverse reactions (e.g., hepatotoxicosis, gastrointestinal disorders, and renal injury) are partly due to ...
Flavia Girolami +5 more
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Aplasia Cutis Congenita Associated with the Use of Antithyroid Medications during Pregnancy: A Case Report [PDF]
Background: Aplasia Cutis Congenita (ACC) is a rare malformation characterized by localized congenital absence of the skin which was first described by Cordon in 1767. ACC is estimated to occur in approximately 1 to 3 cases in 10000 live births.
Pham Chi Kong, Huynh Nhat, Le Chi
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Effects of Thymoquinone on Hypothalamic NPY and AgRP Gene Expression in Intact and Hypothyroidism- Model Rats [PDF]
Background & Objective: Thymoquinone is the most important compound of Nigella sativa, which stimulates the activity of thyroid axis in healthy individuals and people with hypothyroidism.
Nasrin Ghahremani, Fariba Mahmoudi
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Morphological changes in liver of methimazole treated rats, a pilot study
BACKGROUND & OBJECTIVE: Thyrotoxicosis is a disease in which thyroid hormones are raised, and we have seen multiple patients suffering from this ailment in Pakistan. Methimazole is an anti-thyroid drug for thyrotoxicosis.
Maira Bhatti +5 more
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Graves’ disease, a typical metabolism disorder, causes diffuse goiter accompanied by ocular abnormalities and ocular dysfunction. Although methimazole (MI) is a commonly used drug for the treatment of GD, the efficacy of methimazole is only limited to ...
Zhe Han +8 more
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Scalable Process of Methimazole
Base hydrolysis of imidazole carboxylate was observed to be an efficient route for the scalable synthesis of the antithyroid drug methimazole. Ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate (12) was produced as a key intermediate in the ...
Naresh Kumar Katari (14266453) +4 more
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Zinc(II)-methimazole complexes: synthesis and reactivity [PDF]
The tetrahedral S-coordinated complex [Zn(MeImHS)(4)](ClO4)(2), synthesised from the reaction of [Zn(ClO4)(2)] with methimazole (1-methyl-3H-imidazole-2-thione, MeImHS), reacts with triethylamine to yield the homoleptic complex [Zn(MeImS)(2)] (MeImS ...
LIPPOLIS, VITO +19 more
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A rare combination of congenital anomalies following in utero methimazole exposure
The use of methimazole for the treatment of hyperthyroidism in the first trimester of pregnancy has been linked to several congenital malformations. Most commonly reported is choanal atresia; however, other anomalies have been described including aplasia
Taylor Shaw +4 more
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BACKGROUND: The efficacy of anti-thyroid drugs in conjunction with radioactive iodine therapy in the management of Graves’ disease is still controversial.
Ikeoluwapo Kendra Bolakale-Rufai +3 more
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The efficacy of a unique topical dose of methimazole in cats – A case presentation
Methimazole or thiamazole is the most commonly used remedy in the medical management of hyperthyroidism, an endocrine disorder with growing prevalence, particularly in geriatric feline patients. Unfortunately, veterinarians have little, or most often, no
Andreea Pap +5 more
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