Results 161 to 170 of about 134,056 (383)

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang   +18 more
wiley   +1 more source

High Pressure Restrains the Photo‐Induced Polyhedra Distortion in 0D Antimony‐Based Metal Halide

open access: yesAdvanced Science, EarlyView.
0D antimony‐based metal halide (TTA)2SbCl5, exhibits dual emission at 303 nm excitation and a single emission peak at 355 nm excitation. From a high‐pressure perspective and in conjunction with density functional theory calculations, it is shown that the excitation‐dependent emission phenomenon in this is associated with photo‐induced polyhedra ...
Jiaxiang Wang   +6 more
wiley   +1 more source

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

open access: yesAdvanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park   +9 more
wiley   +1 more source

Near Room‐Temperature Ferromagnetic Phase Achieved in 4d Ruthenate via Interfacial Ferrimagnetic Coupling and Octahedral Rotation Engineering

open access: yesAdvanced Science, EarlyView.
Transition metal oxides combining strong spin‐orbit coupling, near‐room‐temperature ferromagnetism, and high conductivity are rare. A Ca0.5Sr0.5RuO3 interfacial phase between LaMnO3 layers has all these features, high Tc, enhanced magnetization, and reduced coercivity.
Mengqin Wang   +10 more
wiley   +1 more source

Smart Health Evaluation for Lithium‐Ion Battery With Super‐Short‐Segment Charging

open access: yesAdvanced Science, EarlyView.
This study proposes a health feature extraction method integrating degradation mechanism‐guided scale‐invariant feature transform with machine learning for lithium‐ion batteries. Validated across 87 commercial cells with diverse chemistries and formats, it achieves 1.97% RMSE in capacity estimation using only 10% charging segments. The approach enables
Qinghua Li   +6 more
wiley   +1 more source

Prosodie et prosodie musicale

open access: yesLa Bretagne Linguistique, 1993
How do the language and its accentuation adapt to the constraints of the melody? Which of these two elements takes precedence in the development of a song? The aim of musical prosody is to highlight the relationship between the accentuation of the lyrics and the melody.
openaire   +1 more source

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