Results 111 to 120 of about 311,944 (266)

D7.3 Report on simulator test results and driver acceptance of PROSPECT functions [PDF]

open access: yes, 2018
The process of developing new automotive systems includes various testing cycles to assure a save operation in traffic. Physical system testing on test tracks is very important for this purpose, but rather expensive and might only become possible in ...
GOHL, Irene   +15 more
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Cumulative Prospect Theory and the St.Petersburg Paradox [PDF]

open access: yes
We find that in cumulative prospect theory (CPT) with a concave value function in gains, a lottery with finite expected value may have infinite subjective value. This problem does not occur in expected utility theory.
Rieger, Marc Oliver, Wang, Mei
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Priorities and prospect theory [PDF]

open access: yes
Most would agree that priority setting is necessary to avoid a financial collapse in the health sector. It is much harder to find criteria how to do it. Discussions lead straight to the principles of decision making.
Happich, Michael
core  

jbferet/prospect: JOSS publication

open access: yes
<p>prospect v1.6.0 was released following the submission, review and correction/improvements of the package and documentation, prior to publication in the Journal of Open Source Software</p ...
floriandeboissieu, jbferet
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Status quo and prospect of transdisciplinary cooperation in rehabilitation of dysphagia

open access: yesHuli yanjiu, 2016
Compared with the United States,Japan and other developed countries,transdisciplinary cooperation of rehabilitation of dysphagia in China was still in the initial stage.This article introduced the concept,and epidemiology of dysphagia,status quo of ...
刘祚燕, 龙纳, 王凤英, 胡秀英
doaj  

Domestic Resource Mobilisation for Sustainable Healthcare Financing in Nigeria: A Review

open access: yesNigerian Postgraduate Medical Journal
Domestic resource mobilisation (DRM) is vital for achieving sustainable healthcare financing in Nigeria, where dependence on external funding and oil revenues has long hindered health sector progress.
Amina Idris Bello   +3 more
doaj   +1 more source

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