Results 41 to 50 of about 4,459,837 (286)

Design of the 18-year follow-up of the Danish COPSAC2000 birth cohort

BMJ Paediatrics Open
Background Atopic diseases, obesity and neuropsychiatric disorders are lifestyle-related and environmental-related chronic inflammatory disorders, and the incidences have increased in the last years.Objective To outline the design of the 18-year follow ...
Anne-Marie Nybo Andersen, Katrine Strandberg-Larsen, Jonathan Groot, Klaus Bønnelykke, Jakob Stokholm, Rebecca Vinding, Bo Chawes, Marianne Mikkelsen, Ann-Marie Malby Schoos, Nicklas Brustad, Trine Mølbæk-Engbjerg, Nilo Vahman, Nadia Rahman Fink, Emil Dalgaard Christensen, Lærke Sass, Hedda Løvenhøj   +15 more
doaj   +1 more source

Maturation of the gut microbiome and risk of asthma in childhood

Nature Communications, 2018
Colonization of commensal bacteria is thought to impact immune development, especially in the earliest years of life. Here, the authors show, by analyzing the development of the gut microbiome of 690 children, that microbial composition at the age of 1 ...
Jakob Stokholm, Martin J. Blaser, Jonathan Thorsen, Morten A. Rasmussen, Johannes Waage, Rebecca K. Vinding, Ann-Marie M. Schoos, Asja Kunøe, Nadia R. Fink, Bo L. Chawes, Klaus Bønnelykke, Asker D. Brejnrod, Martin S. Mortensen, Waleed Abu Al-Soud, Søren J. Sørensen, Hans Bisgaard   +15 more
doaj   +1 more source

Exposures to perfluoroalkyl substances and asthma phenotypes in childhood: an investigation of the COPSAC2010 cohortResearch in context

EBioMedicine, 2023
Summary: Background: Exposure to perfluoroalkyl substances may affect offspring immune development and thereby increase risk of childhood asthma, but the underlying mechanisms and asthma phenotype affected by such exposure is unknown.
Astrid Sevelsted, Casper-Emil Tingskov Pedersen, Gözde Gürdeniz, Morten Arendt Rasmussen, Jörg Schullehner, Kalliroi Sdougkou, Jonathan W. Martin, Jessica Lasky-Su, Andreanne Morin, Carole Ober, Ann-Marie Malby Schoos, Jakob Stokholm, Klaus Bønnelykke, Bo Chawes, Hans Bisgaard   +14 more
doaj   +1 more source

Self-reported health and cardiovascular reactions to psychological stress in a large community sample: Cross-sectional and prospective associations [PDF]

, 2009
Exaggerated cardiovascular reactions to acute psychological stress have been implicated in a number of adverse health outcomes. This study examined, in a large community sample, the cross-sectional and prospective associations between reactivity and ...
Adams, Allen, Allison, Arumugam, Barnett, Bogers, Calle, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Christenfeld, Davis, Edwards, Ford, Goldbacher, Grant, Hemingway, Hirani, Idler, Idler, Idler, Kamarck, Kibler, Kramarow, Leslie, Lovallo, Lynch, Markovitz, Matthews, Mokdad, Newman, O'Brien, Registrar General., Ring, Roy, Schwartz, Shevchuk, Stevens, Strike, Treiber, Waldstein, Willemsen, Winzer, Wulsin, York   +48 more
core   +2 more sources

Higher Education: a once-in-a-lifetime purchase [PDF]

, 2020
Purpose - Drawing on infrequent purchase and university selection literature, this study aims to make theoretical contributions to the identification and comprehension of the ‘once-in-a-lifetime purchase’ (OILP) phenomenon.
Balmer, John, Yang, Hsiao-Pei, Yen , Dorothy   +2 more
core   +1 more source

Infant gut anellovirus composition associates with early life factors and childhood atopic disease

Nature Communications
Anelloviruses are single-stranded circular DNA viruses that infect eukaryotic cells. They are acquired in infancy and can be found in most body compartments.
Ulrika Boulund, Jonathan Thorsen, Frej Larsen, Casper S. Poulsen, Michael Widdowson, Jie Jiang, Kaare Tranæs, Ling Deng, Morten Arendt Rasmussen, Bo Chawes, Klaus Bønnelykke, Dennis S. Nielsen, Shiraz A. Shah, Jakob Stokholm   +13 more
doaj   +1 more source

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers, Chantal Éthier, Caroline Laverdière, Nathalie Alos, Thai Hoa Tran, Marie‐Claude Pelland‐Marcotte   +5 more
wiley   +1 more source

Longitudinal metabolome profiling from pregnancy through childhood and risk of neurodevelopmental disorders at age 10

Nature Communications
Neurodevelopmental disorders (NDD) are characterized by impairments in brain development that affect motor and cognitive systems. Early identification of NDD risk factors is crucial for prevention.
Tingting Wang, Jens Richardt Møllegaard Jepsen, Rebecca Vinding, Nicklas Brustad, Liang Chen, María Hernández-Lorca, Mina Ali, Julie Bøjstrup Rosenberg, Parisa Mohammadzadeh, Michael Widdowson, Parvaneh Ebrahimi, Morten A. Rasmussen, Jonathan Thorsen, Klaus Bønnelykke, Bjørn H. Ebdrup, Bo Chawes   +15 more
doaj   +1 more source

L’épidémie de poliomyélite de 1948-1949 : chamanisme, force vitale et auto-sacrifice chez les Inuit du Kivalliq

Revue d'Études Autochtones, 2022
À l’automne 1948, une « maladie étrange » fait son apparition à Igluligaarjuk (Chesterfield Inlet), un petit village de la baie d’Hudson. Les Soeurs Grises en charge de l’hôpital sont les premières à sonner l’alerte.
Frédéric Laugrand
doaj   +1 more source

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou, Regina Kubica, Karen Fischhuber, Jasmin Beygo, Madlen Reschke, Petra Ritter‐Sovinz, Eva Biewald, Petra Ketteler, Dietmar Lohmann, Deniz Kanber   +9 more
wiley   +1 more source