Results 161 to 170 of about 1,685,573 (358)

Duhok acromegaly; a prospective cohort study

Advanced medical journal, 2017
Background and objectives:Acromegaly is a rare hormonal disorder; the prevalence is around 60 cases/ million population, incidence is3.3new cases/million/year. Mortality rate 2 to 4 times that of general population. It is usually the result of a somatotrope adenoma in more than 95% of cases.The aim is to study our patient`s characteristics, to identify
openaire   +2 more sources

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

The role of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (nhhr) in prediabetes progression and the mediating effect of BMI: a longitudinal study in China

Diabetology & Metabolic Syndrome
Background Diabetes prevalence in China is significant, with a large proportion in the prediabetes stage. Dyslipidemia is associated with abnormal glucose metabolism, and the non-high-density lipoprotein cholesterol to high-density lipoprotein ...
Sichun Wen, Jingfen Li, Zheng Xie, Xiaohui Chen, Junyi Li, Xiayi Lin   +5 more
doaj   +1 more source

Migraine with and without aura in relation to the menstrual cycle and other hormonal milestones: A prospective cohort study [PDF]

, 2023
Iris E. Verhagen, Britt W. H. van der Arend, Daphne S. van Casteren, Niels J S Thiermann, E. Tange, Antoinette MaassenVanDenBrink, Gisela M. Terwindt   +6 more
openalex   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Long-lasting T-cell response to SARS-CoV-2 antigens after vaccination—a prospective cohort study of HCWs working with COVID-19 patients

, 2022
Anders Krifors, Elisabeth Freyhult, Mulki Rashid Teljebäck, Robert P. A. Wallin, Ola Winqvist, Emeli Månsson   +5 more
openalex   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Longitudinal profiling of gut microbiota dynamics in kidney transplant recipients

Journal of Translational Medicine
Background The gut microbiota undergoes substantial alterations in kidney transplant recipients, which are linked to postoperative complications and renal function recovery. However, the underlying mechanisms of these associations remain unclear. Methods
Weibo Zhong, Runtao Feng, Haoxin Liang, Jianmin Hu, Song Zhou, Ding Liu, Shichao Li, Guorong Liao, Jun Liao, Siqiang Yang, Ya Zhang, Xinyun Xiao, Jun Qian, Hua Chen, Lipei Fan, Min Li, Ming Zhao, Jianrong Chen, Yongguang Liu   +18 more
doaj   +1 more source

Optimising diagnostics to discriminate complicated from uncomplicated appendicitis: a prospective cohort study protocol [PDF]

, 2022
Wouter J Bom, Jochem C G Scheijmans, Sander Ubels, Anna A. W. van Geloven, Sarah L. Gans, Kristien M.A.J. Tytgat, Charles C. van Rossem, Lianne Koens, Jaap Stoker, Willem A. Bemelman, Marcel G. W. Dijkgraaf, Marja A. Boermeester   +11 more
openalex   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source