Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Ultra-Processed Food Intake and Risk of Type 2 Diabetes Mellitus: A Dose-Response Meta-Analysis of Prospective Studies (Diabetes Metab J 2025;49:1064-74). [PDF]
Kim Y, Oh H.
europepmc +2 more sources
AI-Assisted Handheld Echocardiography by Nonexpert Operators: A Narrative Review of Prospective Studies. [PDF]
Shittu HA, Quaye PS.
europepmc +1 more source
U.K. Prospective Diabetes Study
Turner, R, Cull, C, Holman, R
openaire +2 more sources
Role of Mitomycin-C in Prevention of Post Operative Adhesions After Endoscopic Sinus Surgery––A Prospective Study [PDF]
Tilakraj Singh, Himani Lade, V. Natesh
openalex +1 more source
Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian +9 more
wiley +1 more source
Second-generation capsule endoscopy for the detection of colorectal polyps: An updated systematic review and comparative meta-analysis of prospective studies. [PDF]
Câmara CF +8 more
europepmc +1 more source
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley +1 more source
The circulating proteome and cancer risk: a systematic literature review and meta-analysis of 26 prospective studies with genetic validation. [PDF]
Dillman A +8 more
europepmc +1 more source

