Results 31 to 40 of about 33,811 (292)

Injury of an aberrant internal carotid artery after myringotomy

open access: yesThe Pan African Medical Journal, 2017
A massive bleeding from the right ear, the nose and from the mouth occurred in a 46-year-old female after ambulatory myringotomy was performed in order to treat symptoms mimicking a persisting middle ear effusion with conductive hearing loss. The patient
Aryé Weinberg, Andreas Eberhard Albers
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

[Oiseau] : [estampe] / [Prosper Alphonse Isaac] [PDF]

open access: yes
Référence bibliographique : IFF19 Isaac (Prosper-Alphonse), 17Appartient à l’ensemble documentaire : FranceJp0Papier à ...
Isaac, Prosper Alphonse (1858-1924). Graveur
core   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

[Poule] : [estampe] / J [Prosper Alphonse Isaac] [monogr.] [PDF]

open access: yes, 1908
Référence bibliographique : IFF19 Isaac (Prosper-Alphonse), 18Appartient à l’ensemble documentaire ...
Isaac, Prosper Alphonse (1858-1924). Graveur
core  

PENGARUH PROFITABILITAS TERHADAP NILAI EMITEN SYARIAH DI INDONESIA

open access: yesJurnal Ilmu Keuangan dan Perbankan, 2022
The main task of the management of a public company is to prosper the shareholders. This is reflected in the increase in the value of the company.This study was conducted to determine the effect of profitability, especially Return on Assets (ROA)
Yoyok Prasetyo   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Prosper Weil and the Mask of Classicism

open access: yesAJIL Unbound, 2020
Prosper Weil's scintillating intervention of 1983 warned against pathological doctrinal tendencies that threatened to “disable international law from fulfilling what have always been its proper functions.” Weil concluded his sweeping critique of these ...
John Tasioulas
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

[Scarabée] : [estampe] / J [Prosper Alphonse Isaac] [monogr.] [PDF]

open access: yes, 1908
Référence bibliographique : IFF19 Isaac (Prosper-Alphonse), 17Appartient à l’ensemble documentaire ...
Isaac, Prosper Alphonse (1858-1924). Graveur
core  

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