Results 41 to 50 of about 33,811 (292)
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Les capucins : [estampe] / [Prosper Alphonse Isaac] [PDF]
, 1908 Référence bibliographique : IFF19 Isaac (Prosper-Alphonse), 4Appartient à l’ensemble documentaire ...
Isaac, Prosper Alphonse (1858-1924). Graveur
core
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
[Cygne] : [estampe] / J [Prosper Alphonse Isaac] [monogr.] [PDF]
, 1908 Référence bibliographique : IFF19 Isaac (Prosper-Alphonse), 11Appartient à l’ensemble documentaire ...
Isaac, Prosper Alphonse (1858-1924). Graveur
core
Klippel-Feil syndrom: a duplicated thumb
The Pan African Medical Journal, 2018 A 71-year-old woman was admitted to our hospital because of a vertigo. At clinical examination a duplicated right thumb was noticed. The Patient revealed that she was suffering from Klippel-Feil Syndrom (KFS).
Aryé Weinberg, Andreas Eberhard Albers
doaj +1 more source
Arthritis Care &Research, EarlyView.Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu +2 more
wiley +1 more source
An ensemble penalized regression method for multi-ancestry polygenic risk prediction
Nature CommunicationsGreat efforts are being made to develop advanced polygenic risk scores (PRS) to improve the prediction of complex traits and diseases. However, most existing PRS are primarily trained on European ancestry populations, limiting their transferability to ...
Jingning Zhang +10 more
doaj +1 more source
Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy. [PDF]
PLoS ONE, 2012 Statin therapy reduces the risk of coronary heart disease (CHD), however, the person-to-person variability in response to statin therapy is not well understood.
Dov Shiffman +17 more
doaj +1 more source
Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis
Arthritis Care &Research, EarlyView.Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs (VA) Rheumatoid Arthritis Registry. Frailty was measured using the VA Frailty Index (VAFI).
Katherine D. Wysham +14 more
wiley +1 more source