Evaluation of coexpression of microsomal prostaglandin E synthase-1 and cyclooxygenase-2 in interleukin-1– stimulated equine articular chondrocytes [PDF]
Judith Farley +4 more
openalex +1 more source
Microsomal prostaglandin E synthase-1 (mPGES-1) [PDF]
openaire +1 more source
Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li +5 more
wiley +1 more source
Prostaglandin F<sub>2α</sub> exacerbates ovalbumin-induced chronic pneumonia and attenuates depression in mice. [PDF]
Maehara T +4 more
europepmc +1 more source
Metabolism‐Regulating Nanomedicines for Cancer Therapy
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source
A phase 2 trial investigating the efficacy and safety of the mPGES-1 inhibitor vipoglanstat in systemic sclerosis-related Raynaud's. [PDF]
Tornling G +18 more
europepmc +1 more source
Microsomal Prostaglandin E Synthase Is Regulated by Proinflammatory Cytokines and Glucocorticoids in Primary Rheumatoid Synovial Cells [PDF]
Dirk O. Stichtenoth +5 more
openalex +1 more source
Microsomal prostaglandin E synthase-1 (mPGES-1) [PDF]
openaire +1 more source
Research Progress of Ferroptosis in Cerebral Infarction
Cerebral infarction triggers ischemia–reperfusion injury, leading to iron overload, oxidative stress, and mitochondrial dysfunction, which together initiate ferroptosis—an iron‐dependent, lipid peroxidation–driven form of neuronal death. Disruption of the System Xc−/GSH/GPX4 antioxidant axis and ACSL4‐mediated PUFA phospholipid enrichment accelerates ...
Yilan Fei, Qi Leng
wiley +1 more source

