Microsomal Prostaglandin E Synthase-1 Is Overexpressed in Inflammatory Bowel Disease [PDF]
Kotha Subbaramaiah+9 more
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Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes. [PDF]
Hassan Afif+4 more
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A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia+4 more
wiley +1 more source
Prostaglandin E2 Is a Product of Induced Prostaglandin-endoperoxide Synthase 2 and Microsomal-type Prostaglandin E Synthase at the Implantation Site of the Hamster [PDF]
Xiaohong Wang+6 more
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Diagnostics of Autoimmune Hepatitis Enabled by Non‐Invasive Clinical Proteomics
Mass‐spectrometry‐based proteomic analyses of paired liver‐plasma samples from patients with AIH enabled discovery of numerous proteins showing high diagnostic accuracy. Proteomics may constitute a novel non‐invasive diagnostic tool for AIH if validated in larger, age‐ and sex‐matched cohorts.
Anne‐Sofie Houlberg Jensen+20 more
wiley +1 more source
Vascular endothelial growth factor increases messenger RNAs encoding cyclooxygenase-II and membrane-associated prostaglandin E synthase in rat luteal cells [PDF]
Toshihiro Sakurai+2 more
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Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen+9 more
wiley +1 more source
Effects of Interleukin-1β and Prostaglandin E2on Prostaglandin D Synthase Production in Cultivated Rat Leptomeningeal Cells [PDF]
Takeshi Muraki+6 more
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Diabetic nephropathy (DN) is a major complication of diabetes, leading to end‐stage renal disease. This study identified 109 differentially expressed genes (DEGs) and validated LOX as a novel diagnostic biomarker through integrated bioinformatics and experimental analysis.
Shahad W. Kattan+11 more
wiley +1 more source