Results 121 to 130 of about 348,697 (337)

Regulation of Chondrocyte Metabolism and Osteoarthritis Development by Sirt5 Through Protein Lysine Malonylation

Arthritis &Rheumatology, EarlyView.
Objective Chondrocytemetabolic dysfunction plays an important role in osteoarthritis (OA) development during aging and obesity. Protein posttranslational modifications (PTMs) have recently emerged as an important regulator of cellular metabolism. We aim to study one type of PTM, lysine malonylation (MaK), and its regulator sirtuin 5 (Sirt5) in OA ...
Huanhuan Liu, Anupama Binoy, Siqi Ren, Thomas C. Martino, Anna E. Miller, Craig R. G. Willis, Shivakumar R. Veerabhadraiah, Joanna Bons, Jacob P. Rose, Birgit Schilling, Michael J. Jurynec, Shouan Zhu   +11 more
wiley   +1 more source

Gout and NLRP3 Inflammasome Biology

Arthritis &Rheumatology, EarlyView.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source

Regulation of Immune Responses by Prostaglandin E2

Journal of Immunology, 2012
P. Kalinski
semanticscholar   +1 more source

On the Mechanism of the Biosynthesis of Prostaglandins E1 and F1α

, 1967
Mats Hámberg, Bengt Samuelsson
openalex   +1 more source

THE OCCURRENCE OF PROSTAGLANDIN E₂ IN SPLENIC VENOUS BLOOD OF THE DOG FOLLOWING SPLENIC NERVE STIMULATION [PDF]

, 1968
B. N. Davies, E. W. HORTON, P.G. Withrington   +2 more
openalex   +1 more source

Changes in Pain Sensitization after DMARD therapy are Associated with Changes in Disease Activity in Established Rheumatoid Arthritis

Arthritis &Rheumatology, Accepted Article.
Objective Abnormalities in pain regulatory mechanisms are common in patients with rheumatoid arthritis (RA). We investigated whether pain sensitization changes after treatment with a disease modifying anti‐rheumatic drug (DMARD) and explored associations between changes in pain sensitization and disease activity.
Burcu Aydemir, Andrew C. Heisler, Lutfiyya N. Muhammad, Jing Song, Alyssa Wohlfahrt, Daniel J. Clauw, Wendy Marder, Marcy B. Bolster, Clifton O. Bingham, Tuhina Neogi, Yvonne C. Lee   +10 more
wiley   +1 more source

A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

Proceedings of the National Academy of Sciences of the United States of America, 1990
J. Morrow, K. Hill, R. Burk, T. M. Nammour, K. Badr, L. Roberts   +5 more
semanticscholar   +1 more source

Antifertility Properties of Prostaglandin F2α [PDF]

, 1969
Garance Gutknecht, James C. Cornette, Bruce B. Pharriss   +2 more
openalex   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing.

Proceedings of the National Academy of Sciences of the United States of America, 1991
Weilin Xie, J. Chipman, D. L. Robertson, R. Erikson, D. Simmons   +4 more
semanticscholar   +1 more source