Results 121 to 130 of about 345,095 (348)
Mass Spectrometry Reviews, EarlyView., 2023 Abstract Biodegradable polymers have been getting more and more attention because of their contribution to the plastic pollution environmental issues and to move towards a circular economy. Nevertheless, biodegradable materials still exhibit various disadvantages restraining a widespread use in the market.
Paola Rizzarelli +2 more
wiley +1 more source
Cytoprotection by prostaglandins
Gastroenterology, 1979 Prostaglandins (PG) are a group of ZO-carbon oxy- genated fatty acids that are present in most mamma- lian cells and tissues. Approximately 20 of these chemicals have been identified in tissues and body fluids, whereas hundreds have been synthesized as analogs or derivatives of the natural PG.
openaire +4 more sources
ChemMedChem, EarlyView.By N‐methylation, the intramolecular lactam formation in carborane‐substituted diclofenac analogs is prevented, yielding a series of open‐chain derivatives alongside with their phenyl analogs exhibiting anticancer activity and thus offering a promising avenue for future drug development. This study explores the anticancer potential of N‐methylated open‐
Christoph Selg +12 more
wiley +1 more source
Effect of prostaglandin E1 on the strychnine-induced convulsion in the mouse [PDF]
, 1969 Suna Duru, R. K. Türker
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Synthesis and Biological Evaluation of Bicyclic Pyrazolines with Promising Antimicrobial Activities
ChemMedChem, EarlyView.Continuous flow technology is exploited for the generation of bicyclic pyrazolines via photo‐click reactions. These heterocyclic species contain a valuable 3D scaffold along with a polar succinimide moiety. Subsequent antimicrobial testing reveals that halogenated moieties such as chlorine atoms and trifluoromethoxy groups enhance the potency of these ...
Debora Caviglia +4 more
wiley +1 more source
ChemMedChem, EarlyView.Eight nido‐ and ortho‐carborane compounds based on celecoxib and flurbiprofen were synthesized and their COX inhibition was determined. The deboronation of the di‐substituted celecoxib derivative results in a switch from COX‐1 inhibitory preference to COX‐2 inhibition.
Lea Ueberham +8 more
wiley +1 more source
DISTRIBUTION OF PROSTAGLANDINS IN HUMAN TISSUES [PDF]
, 1967 S.M.M. Karim, M. Sandler, E. D. Williams
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ChemSusChem, Accepted Article.Hydroxylated derivatives of arachidonic acid play crucial roles in physiology and inflammation response, with distinct biological effects for (R)‐ and (S)‐enantiomers, highlighting their pharmaceutical relevance. Here, we harness recombinant unspecific peroxygenases (UPOs)—from the fungi Coprinopsis cinerea (rCciUPO) and Agrocybe aegerita (rAaeUPO ...
Alejandro González-Benjumea +7 more
wiley +1 more source
A COMPARISON OF THE ACTIONS OF PROSTAGLANDINS F2a AND E1 ON SMOOTH MUSCLE [PDF]
, 1965 E. W. HORTON, I H Main
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