Expression of cyclo-oxygenase 1 and 2, prostaglandin E synthase and transforming growth factor β1, and their relationship with vascular endothelial growth factors A and C, in primary adenocarcinoma of the small intestine [PDF]
, 2006 Burkhard H.A. von Rahden +5 more
openalex +1 more source
"Pharmacology of salicin derivatives in sheep" : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand [PDF]
, 2016 Content removed from thesis due to copyright reasons: Figure 1.20(e). S. viminalis. Retrieved from Valerie J.:http://gardeners-word.blogspot.co.uk/Sheep suffer from pain during various husbandry practices as well as during injury or diseases such as ...
Mathurkar, Shashwati Chandrakant
core
Prothrombotic Activation of Platelet Pannexin‐1 Channels in Antiphospholipid Syndrome
Arthritis &Rheumatology, EarlyView.Objective ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. The objective of this study was to evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired ...
Bruna de Moraes Mazetto Fonseca +13 more
wiley +1 more source
Navigating adverse immunostimulation: A practical guide for clinical researchers
British Journal of Clinical Pharmacology, EarlyView.Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort +3 more
wiley +1 more source
Reproductive Medicine and BiologyBackground Endometriosis is a challenging disease to treat and one of the leading causes of infertility. Impaired endometrial receptivity, and particularly inadequate decidualization of endometrial stromal cells (ESCs), is a crucial component.
Kazuhiro Tamura +3 more
doaj +1 more source
Prostaglandin‐Independent Stimulation of Interleukin‐6 Production by Fibrinogen Degradation Product D in Perfused Murine Liver [PDF]
, 1998 Miklós Csala +8 more
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Activation of Extracellular-signal Regulated Kinase (ERK1/2) by Fluid Shear is Ca\u3csup\u3e2+\u3c/sup\u3e- and ATP-dependent in MC3T3-E1 Osteoblasts [PDF]
, 2008 To determine the role of Ca2+ signaling in activation of the Mitogen-Activated Protein Kinase (MAPK) pathway, we subjected MC3T3-E1 pre-osteoblastic cells to inhibitors of Ca2+ signaling during application of fluid shear stress (FSS).
Duncan, Randall L. +7 more
core +1 more source
Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta‐analysis
British Journal of Clinical Pharmacology, EarlyView.Aim The purpose of this study is to estimate the risk of gastrointestinal bleeding (GIB) by selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) individual agents. Methods A systematic review was conducted for each unique antidepressant (i.e.
Ainhoa Gomez‐Lumbreras +8 more
wiley +1 more source
Novel prostaglandin and isoprostane panel for evaluating Wilson’s Disease
Türk Biyokimya DergisiWilson’s disease (WD) leads to copper accumulation in the liver and brain. It generates oxidative stress, which can damage the liver and central nervous system (CNS). The concentrations of oxidized lipid products, such as prostaglandins and isoprostanes,
Polat Merve Banu +10 more
doaj +1 more source