Results 141 to 150 of about 347,774 (279)

Metabolomic and lipidomic signatures of Helicobacter pylori infection: Unveiling biochemical pathways associated with neurodegeneration

iMetaOmics, EarlyView.
Our study employed an integrated lipidomics and metabolomics approach to elucidate Helicobacter pylori‐driven metabolic perturbations along the gut–brain axis. H. pylori infection was established in gastric epithelial (AGS) cells, and the resulting conditioned media (secretome) was collected and exposed to neuronal (IMR‐32) cells.
Meenakshi Kandpal, Tarun Prakash Verma, Siddharth Singh, Hamendra Parmar, Hem Chandra Jha   +4 more
wiley   +1 more source

Intravenous Prostaglandin F2alpha for the Induction of Labor at a Japanese Perinatal Center. [PDF]

Cureus
Yokoyama N, Haruna Y, Suzuki S.
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Prostaglandin analog therapy challenges and innovation in glaucoma therapeutics. [PDF]

Indian J Ophthalmol
Nath M, Alam K, Halder N, Dada T, Thirumurthy V.   +4 more
europepmc   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Evaluation of Risk Factors for Unilateral Aponeurotic Ptosis Using the Fellow Eye as Control: A Retrospective Study. [PDF]

Clin Ophthalmol
Katsuo A, Iwasaki K, Takayanagi R, Tanaka N, Suzuki M, Arimura S, Takamura Y, Inatani M.   +7 more
europepmc   +1 more source

Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini, Francesca Caloni, Paola Fossati, Giancarlo Ruffo, Luciana Rossi   +4 more
wiley   +1 more source

Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies. [PDF]

Front Pharmacol
Torres de Souza G, Williams G, Vicente Silva CC, Chiovatto CB, Epstein GK, Vila-Vecilla L, Russo V.   +6 more
europepmc   +1 more source

The Application Value of Transvaginal Three‐Dimensional Ultrasonography in the Diagnosis of Adenomyosis of the Uterus

Journal of Clinical Ultrasound, EarlyView.
In this study, 3D‐TVS measurements of the uterine junction zone (JZ) in 120 patients showed that a JZmax threshold of ≥ 0.45 cm yielded 77% sensitivity and 89% specificity for adenomyosis diagnosis. Notably, JZ thickness varies minimally with age, demonstrating its stability and excellent diagnostic performance.
Mengyu Li, Zhen Zong, Xiaoman Wang, Hebin Zhang   +3 more
wiley   +1 more source

Dynamic changes of the immune microenvironment in ovarian cancer following neoadjuvant chemotherapy. [PDF]

Cell Death Discov
Wu M, Lv F, Jin Y, Wang S, Meng L, Tong J, Zou R.   +6 more
europepmc   +1 more source