Results 141 to 150 of about 501,484 (388)
Journal of Biological Chemistry, 2000 Here we report the molecular identification of cytosolic glutathione (GSH)-dependent prostaglandin (PG) E2 synthase (cPGES), a terminal enzyme of the cyclooxygenase (COX)-1-mediated PGE2 biosynthetic pathway. GSH-dependent PGES activity in the cytosol of
T. Tanioka +4 more
semanticscholar +1 more source
Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source
Advanced Maternal Age Worsens Postpartum Vascular Function
Frontiers in Physiology, 2017 The age at which women experience their first pregnancy has increased throughout the decades. Pregnancy has an important influence on maternal short- and long-term cardiovascular outcomes.
Jude S. Morton +10 more
doaj +1 more source
Phospholipid precursors of prostaglandins [PDF]
, 1968 William E.M. Lands, Bengt Samuelsson
openalex +1 more source
The Structure of Prostaglandin E, F1 and F2. [PDF]
, 1962 Sune Bergström +5 more
openalex +1 more source
A single meal has the potential to alter brain oxylipin content. [PDF]
, 2020 Our objective was to determine whether consumption of a single meal has the potential to alter brain oxylipin content. We examined the cerebrum of mice fed a single high-fat/high-sucrose Western meal or a low-fat/low-sucrose control meal, as well as ...
Aung, HH +5 more
core +1 more source
Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production
Journal of Experimental Medicine, 1995 During human immunodeficiency virus infection and allergic diseases, characterized by a dominant T helper (Th) 2 response, overproduction of prostaglandin E2 (PGE2) is observed. In this paper we studied the effect of PGE2 on interleukin (IL)-12 synthesis,
Tineke C T M Van Der Pouw +5 more
semanticscholar +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
BMEMat, EarlyView.This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu +7 more
wiley +1 more source
The Isolation of Prostaglandin E from Sheep Prostate Glands. [PDF]
, 1960 Sune Bergström +4 more
openalex +1 more source
Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor
Cancer Communications, EarlyView.Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai +6 more
wiley +1 more source