Results 141 to 150 of about 202,856 (298)

Metabolism of Prostaglandins in Rat Liver Mitochondria [PDF]

, 1968
Mats Hámberg
openalex   +1 more source

Spatial Isolation of Single Copper(I) Sites for Cascade Enzyme‐Like Catalysis and Simultaneous Ferroptosis/Cuproptosis Boosted Immunotherapy

Exploration, EarlyView.
Self‐assembled S‐Cu(I)‐S sites were spatially isolated onto a two‐dimensional Ti3C2 surface to produce a structurally well‐defined and highly functional single‐site copper(I) nanomodulator CuNTD, which can induce severe immunogenic cell death through multiple regulatory pathways of synergistic cascade photothermal‐amplified ROS storms, cuproptosis and ...
Yuanyuan Zhang, Shengnan Ya, Jingnan Huang, Yangyang Ju, Xueyang Fang, Xinteng Ouyang, Qingdong Zeng, Xinyao Zhou, Xiyun Yan, Guohui Nie, Kelong Fan, Bin Zhang   +11 more
wiley   +1 more source

Structurally and Functionally Adaptive Biomimetic Periosteum: Materials, Fabrication, and Construction Strategies

Exploration, EarlyView.
Schematic illustration of structural and functional biomimicry. The upper part shows BP with various structures such as monolayered, surface‐microstructural, bilayered and multilayered. The bottom part exhibits BP with different functions including immune regulation, drugs/cells/factors/ions loading, as well as bioelectrical stimulation and ...
Yuhan Du, Yujie Liu, Yuanchi Zhang, Yangyi Nie, Zili Xu, Ling Qin, Wei Zhang, Yuxiao Lai   +7 more
wiley   +1 more source

Developmental pharmacokinetics of indomethacin in preterm neonates: Severely decreased drug clearance in the first week of life

CPT: Pharmacometrics &Systems Pharmacology, Volume 12, Issue 1, Page 110-121, January 2023., 2023
Abstract Indomethacin is used commonly in preterm neonates for the prevention of intracranial hemorrhage and closure of an abnormally open cardiac vessel. Due to biomedical advances, the infants who receive this drug in the neonatal intensive care unit setting have become younger, smaller, and less mature (more preterm) at the time of treatment.
Wojciech Krzyzanski, Bradley Stockard, Andrea Gaedigk, Allison Scott, Whitney Nolte, Kim Gibson, J. Steven Leeder, Tamorah Lewis   +7 more
wiley   +1 more source

CYP4F3B is induced by PGA1 in human liver cells: a regulation of the 20-HETE synthesis

Journal of Lipid Research, 2008
The regulation of the human liver-specific cytochrome P450 4F3B (CYP4F3B) isoform, a splice variant of the CYP4F3 gene with strong substrate specificity for long chain fatty acids, is yet an unsolved question. This report provides the first evidence that
Joseph Antoun, Sophie Goulitquer, Yolande Amet, Yvonne Dreano, Jean-Pierre Salaun, Laurent Corcos, Emmanuelle Plée-Gautier   +6 more
doaj  

Berries: Health Effects via Modulation of the Gut Microbiota

Food Frontiers, EarlyView.
ABSTRACT Berries are widely regarded as beneficial foods, rich in polyphenols, flavonoids, and other bioactive compounds that could positively influence human health. Although the gut microbiota plays a crucial role in metabolism and physiology of humans, the interaction between berries and human gut microbiota activity remains unclear.
Manjin Xu, Yunfeng Xu, Lizhi Wu, Huixia Niu, Bei Gao, Kai Sun, Xueqing Li, Mingluan Xing, Zhe Mo, Zhijian Chen, Pengcheng Tu, Xiaoming Lou   +11 more
wiley   +1 more source

Corrigendum: Lipid Bodies as Sites of Prostaglandin E2 Synthesis During Chagas Disease: Impact in the Parasite Escape Mechanism

Frontiers in Microbiology, 2018
Patrícia E. de Almeida, Daniel A. M. Toledo, Gabriel S. C. Rodrigues, Heloisa D'Avila   +3 more
doaj   +1 more source

Human cyclooxygenase-1 activity and its responses to COX inhibitors are allosterically regulated by nonsubstrate fatty acids

Journal of Lipid Research, 2012
Recombinant human prostaglandin endoperoxide H synthase-1 (huPGHS-1) was characterized. huPGHS-1 has a single high-affinity heme binding site per dimer and exhibits maximal cyclooxygenase (COX) activity with one heme per dimer.
Hechang Zou, Chong Yuan, Liang Dong, Ranjinder S. Sidhu, Yu H. Hong, Dmitry V. Kuklev, William L. Smith   +6 more
doaj  

A COMPARISON OF THE BIOLOGICAL ACTIVITIES OF FOUR PROSTAGLANDINS [PDF]

, 1963
E. W. HORTON, I H Main
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Broccoli and Arthritis: A Review

Food Frontiers, EarlyView.
A dietary supplement of broccoli holds potential as a preventive measure against arthritis due to its widespread popularity, safety profile, and affordability. In this systematic review, we have compiled and summarized relevant literature regarding the effects of broccoli and its major bioactive components on arthritis, along with the underlying ...
Mingyuan Song, Xingquan Xu, Prachi Wele, Ding Wei, Xian Wu, Wenjin Yan   +5 more
wiley   +1 more source