Results 91 to 100 of about 247,667 (300)

Effect of prostaglandin E1 on the permeability response of the isolated collecting tubule to vasopressin, adenosine 3',5'-monophosphate, and theophylline.

Journal of Clinical Investigation, 1968
The effect of prostaglandin E(1) (PGE(1)) on the water permeability response to vasopressin, theophylline, and cyclic adenosine 3',5'-monophosphate (C-AMP) of isolated, perfused collecting tubules of the rabbit was investigated in vitro. Prostaglandin is
J. Grantham, J. Orloff
semanticscholar   +1 more source

PRRX2 Regulates GLI2 to Promote Proliferation, Invasion, and Metastasis by Inhibiting Senescence via Hedgehog Signaling

Cancer Science, EarlyView.
PRRX2 is highly expressed in pancreatic cancer and correlates with patient prognosis. PRRX2 promotes pancreatic cancer cell proliferation, invasion, and metastasis, and inhibits pancreatic cancer cell senescence. PRRX2 transcriptionally regulates GLI2 and activates the Hedgehog pathway.
Wei Huang, Feiqiang xu, Jichuan xu, Gang Quan, Shihang zhang, Mengmeng guo, Feng xiao, Jianxin jiang   +7 more
wiley   +1 more source

Prostaglandins in Cancer Cell Adhesion, Migration, and Invasion

International Journal of Cell Biology, 2012
Prostaglandins exert a profound influence over the adhesive, migratory, and invasive behavior of cells during the development and progression of cancer.
David G. Menter, Raymond N. DuBois
doaj   +1 more source

Management of early pregnancy loss with mifepristone and misoprostol: clinical predictors of treatment success from a randomized trial. [PDF]

, 2020
BackgroundEarly pregnancy loss is a common event in the first trimester, occurring in 15%-20% of confirmed pregnancies. A common evidence-based medical regimen for early pregnancy loss uses misoprostol, a prostaglandin E1 analog, with a dosage of 800 μg,
Atrio, Jessica M, Creinin, Mitchell D, Koelper, Nathanael, McAllister, Arden, Sammel, Mary D, Schreiber, Courtney A, Sonalkar, Sarita   +6 more
core   +1 more source

Prostaglandin E1 Combined with Chitosan Conduit Improves Sciatic Nerve Regeneration in Rats [PDF]

Iranian Journal of Veterinary Surgery, 2017
Objective- To studylocal effect of prostaglandin E1on sciatic nerve regeneration Design- Experimental study Animals- Sixty male healthy white Wistar rats Procedures- Sixty animals were divided into four experimental groups (n = 15), randomly: Trasnsected
Alireza Najafpour
doaj  

Chloride secretory mechanism induced by prostaglandin E1 in a colonic epithelial cell line.

Journal of Clinical Investigation, 1985
Confluent T84 monolayers grown on permeable supports and mounted in a modified Ussing chamber secrete chloride (Cl-) in response to prostaglandin E1. The threshold stimulation was observed at 10(-9) M and a maximal effect at 10(-6) M. Unidirectional flux
Andrew Weymer, P. Huott, Wilson, Liu, James A. McRoberts, Kiertisin Dharmsathaphom   +5 more
semanticscholar   +1 more source

Effects of gestational intermittent hypoxia on the respiratory system: A tale of the placenta, fetus, and developing offspring

Journal of Sleep Research, Volume 34, Issue 4, August 2025.
Effects of gestational intermittent hypoxia on maternal, fetal and offspring respiratory system. In black, effects in humans; in red, in vitro effects; in blue, effects in animal models. Summary Obstructive sleep apnea (OSA) is a common sleep disorder that is associated with a wide variety of health conditions, including cardiovascular, cerebrovascular,
Esther Valverde‐Pérez, Elena Olea, Asunción Rocher, Philip I. Aaronson, Jesús Prieto‐Lloret   +4 more
wiley   +1 more source

Dietary Manganese Modulates Microbiota and Intestinal N‐Acylethanolamines in a Sex‐Specific Manner in Mice With Diet‐Induced Obesity

The FASEB Journal, Volume 39, Issue 13, 15 July 2025.
Female and male mice were fed manganese (Mn)‐depleted or Mn‐enriched diets in combination with either a low fat‐low sucrose (LFLS) or high fat‐high sucrose (HFHS) diet for 28 days. A sex‐specific metabolic response was observed under Mn‐depleted conditions, particularly affecting monoacylglycerol levels.
Fredy Alexander Guevara Agudelo, Nadine Leblanc, Isabelle Bourdeau‐Julien, Gabrielle St‐Arnaud, Fadil Dahhani, Nicolas Flamand, Alain Veilleux, Vincenzo Di Marzo, Frédéric Raymond   +8 more
wiley   +1 more source

Identification of metabolites from peroxisomal beta-oxidation of prostaglandins.

Journal of Lipid Research, 1990
We have recently shown that isolated rat liver peroxisomes can chain-shorten prostaglandin F2 alpha and prostaglandin E2 to tetranor-metabolites. In the present report dinor-metabolites of these two prostaglandins were also identified, suggesting that ...
U Diczfalusy, SE Alexson
doaj  

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, Volume 12, Issue 25, July 3, 2025.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source