Results 151 to 160 of about 394,079 (375)

Prostaglandin pathways in equine myometrium regulations: endometrosis progression

Frontiers in Veterinary Science
IntroductionProstaglandins (PG) are important regulators of the myometrial contractility in mammals. Endometrosis, a condition characterized by morphological changes in the equine endometrium, also affects endometrial secretory function.
Katarzyna K. Piotrowska-Tomala, Anna Z. Szóstek-Mioduchowska, Ewa M. Drzewiecka, Ewa M. Drzewiecka, Agnieszka W. Jonczyk, Anna Wójtowicz, Michał H. Wrobel, Graca Ferreira-Dias, Graca Ferreira-Dias, Dariusz J. Skarzynski   +9 more
doaj   +1 more source

Celecoxib in breast cancer prevention and therapy. [PDF]

, 2018
Breast cancer has a high incidence worldwide. The results of substantial studis reveal that inflammation plays an important role in the initiation, development, and aggressiveness of many malignancies. The use of celecoxib, a novel NSAID, is repetitively
Cao, Wei, Hao, Qiongyu, Li, Jieqing, Vadgama, Jaydutt V, Wu, Yong   +4 more
core  

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Transforming growth factor-beta stimulation of lung fibroblast prostaglandin E2 production. [PDF]

, 1989
Transforming growth factor-beta (TGF beta) stimulated the production of total protein, collagen, and fibronectin by normal human lung fibroblasts.
Diaz, Arturo, Jimenez, Sergio A., Varga, John   +2 more
core   +1 more source

Prostaglandin I2 Attenuates Prostaglandin E2-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent Mechanism [PDF]

, 2016
Pu Wang, Peipei Guan, Xin Yu, Lichao Zhang, Yanan Su, Zhan‐You Wang   +5 more
openalex   +1 more source

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

Clinical &Experimental Allergy, EarlyView.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna, Christina Morgenstern, Katharina Poglitsch, Tamara Arnoldner, Katharina Gangl, Tina J. Bartosik, Nicholas J. Campion, Aldine Tu, Victoria Stanek, Sven Schneider, Christine Bangert   +10 more
wiley   +1 more source

The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review

Epilepsia, EarlyView.
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu, Jules Jeuris, Wim Van Paesschen   +2 more
wiley   +1 more source

Role of phospholipase A2 in the stimulation of sponge cell proliferation by homologous lectin. [PDF]

, 1989
Friese, K., Fritsche, U., Gramzow, M., Kreuter, M., Kurelec, B., Müller, W., Robitzki, A., Schröder, H., Zimmermann, H.   +8 more
core   +1 more source

Celecoxib decreases prostaglandin E\u3csub\u3e2\u3c/sub\u3e concentrations in nipple aspirate fluid from high risk postmenopausal women and women with breast cancer [PDF]

, 2006
Background Celecoxib inhibits PGE2 production in cancerous tissue. We previously reported that PGE2 levels in nipple aspirate fluid (NAF) and plasma were not decreased in women at increased breast cancer risk who received celecoxib 200 mg twice daily ...
Flynn, John T., Hewett, John E., Quin, Wenyi, Sauter, Edward R., Schlatter, Lisa   +4 more
core   +1 more source

Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis [PDF]

, 2022
Eiman Elwakeel, Mirko Brüggemann, Jessica Wagih, Olga Lityagina, Mohammed A.F. Elewa, Yingying Han, Timo Frömel, Rüdiger Popp, Adele M. Nicolas, Yannick Schreiber, Elise Gradhand, Dominique Thomas, Rolf Nüsing, Julia Steinmetz-Späh, Rajkumar Savai, Emmanouil Fokas, Ingrid Fleming, Florian R. Greten, Kathi Zarnack, Bernhard Brüne, Andreas Weigert   +20 more
openalex   +1 more source