Results 291 to 300 of about 384,482 (373)

Cotton Pellet Granulomaのリン脂質代謝におよぼすProstaglandin E2およびF2αの局所投与の影響について

, 1977
山田 健二, 相澤 義雄
openalex   +1 more source

Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and high‐throughput RNA sequencing

British Journal of Pharmacology, Volume 182, Issue 16, Page 3800-3817, August 2025.
Background and Purpose Nimodipine, an L‐type voltage‐gated calcium channel blocker, is an approved cerebral vasorelaxant. We hypothesized that nimodipine attenuates the pro‐inflammatory shift in microglial phenotypes. Here, we analysed the effects of nimodipine on morphological and functional microglial phenotypes as well as their transcriptomic ...
István Pesti, Valentin Varga, Erda Qorri, Rita Frank, Diana Kata, Krisztián Vinga, Péter Archibald Szarvas, Ákos Menyhárt, Károly Gulya, Ferenc Bari, Eszter Farkas   +10 more
wiley   +1 more source

NG2 glia protect against prion neurotoxicity by inhibiting microglia-to-neuron prostaglandin E2 signaling. [PDF]

Nat Neurosci
Liu Y, Guo J, Matoga M, Korotkova M, Jakobsson PJ, Aguzzi A.   +5 more
europepmc   +1 more source

Effects of gestational intermittent hypoxia on the respiratory system: A tale of the placenta, fetus, and developing offspring

Journal of Sleep Research, Volume 34, Issue 4, August 2025.
Effects of gestational intermittent hypoxia on maternal, fetal and offspring respiratory system. In black, effects in humans; in red, in vitro effects; in blue, effects in animal models. Summary Obstructive sleep apnea (OSA) is a common sleep disorder that is associated with a wide variety of health conditions, including cardiovascular, cerebrovascular,
Esther Valverde‐Pérez, Elena Olea, Asunción Rocher, Philip I. Aaronson, Jesús Prieto‐Lloret   +4 more
wiley   +1 more source

Comparative Analysis of Thromboxane B2 (TXB2) and Prostaglandin E2 (PGE2) Levels in the Gingival Crevicular Fluid (GCF) of Diabetic Patients With Chronic Periodontitis: An Enzyme Immunoassay Study. [PDF]

Cureus
Mahale AY, Agarwal S, Bansal R, Khan S, Goyel P, Chaubey A, Gupta S.   +6 more
europepmc   +1 more source

A simple, rapid and simultaneous extraction of thromboxane B2, 6-keto-prostaglandin F1.ALPHA. and prostaglandin E2.

, 1987
Katsumi Kawano, Masuo Sugita, Masanori Oka, Noboru Tabata   +3 more
openalex   +2 more sources

Antitumor efficacy of intermittent low‐dose erlotinib plus sulindac via MHC upregulation and remodeling of the immune cell niche

International Journal of Cancer, Volume 157, Issue 2, Page 355-370, 15 July 2025.
What's new? Novel immunomodulatory insights derived from experimental models and clinical samples reveal the cancer‐preventive potential of intermittent low‐dose erlotinib plus sulindac (ERL + SUL). This study shows that ERL + SUL treatment upregulates MHC class I and II expression and remodels the immune cell niche, with significant tumor suppression ...
Chakrapani Tripathi, Jorge E. Tovar Perez, Sabeeta Kapoor, Ahmed Muhsin, Wan Mohaiza Dashwood, Yunus Demirhan, Melek Demirhan, Alessandro Shapiro, Altaf Mohammed, Shizuko Sei, Jacklyn Thompson, Mahira Zaheer, Krishna M. Sinha, Powel H. Brown, Michelle I. Savage, Eduardo Vilar, Praveen Rajendran, Roderick H. Dashwood   +17 more
wiley   +1 more source

Further Evidence that Accelerated Muscle Protein Breakdown During Sepsis Is Not Mediated by Prostaglandin E2

, 1988
Per‐Olof Hasselgren, Brad W. Warner, Robert P. Hummel, J. Howard James, Cora K. Ogle, Josef E. Fischer   +5 more
openalex   +2 more sources

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis

Advanced Science, Volume 12, Issue 25, July 3, 2025.
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu, Amarnath Marudamuthu, Khadija Kakar, Hamida Hamida, Shruthi Thada, Rohan Gupta, Kiesha Wilson, Taylor Carter, Yin Zhong, Archana Saxena, Xiaoming Yang, Narendra Singh, Philip Brandon Busbee, Jie Li, Monica Garcia‐Buitrago, Prakash Nagarkatti, Mitzi Nagarkatti   +16 more
wiley   +1 more source