An Optimized Ex Vivo n-3 PUFA Supplementation Strategy for Primary Human Macrophages Shows That DHA Suppresses Prostaglandin E2 Formation. [PDF]
Kirchhoff R +5 more
europepmc +1 more source
Metabolism‐Regulating Nanomedicines for Cancer Therapy
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source
The Effect of the Intracervical Application of Follicle-Stimulating Hormone or Luteinizing Hormone on the Pattern of Expression of Gonadotrophin Receptors in the Cervix of Non-Pregnant Ewes [PDF]
Diaz +32 more
core +1 more source
Anti-inflammatory and bronchoprotective roles of endogenous prostaglandin E2
Hiroki Sakakibara
openalex +1 more source
Fabp5 Is the Key Regulator Mediating γ‐CEHC Differentiation in Osteoblasts and Osteoclasts
γ‐CEHC, as a natural Fabp5 inhibitor, ameliorates the osteoporotic microenvironment through a triple‐action mechanism—targeting Fabp5 inhibition → modulating macrophage polarization → balancing bone metabolism—highlighting its translational medical value.
Cheng Cheng +7 more
wiley +1 more source
Prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) in tissue regeneration: Its role and therapeutic strategies. [PDF]
Wang W, Pan K, Yang J, Li Z.
europepmc +1 more source
TANs drive ICI resistance via antitumour immune remodelling, angiogenesis promotion, and elevation of tumour mutation burden Neutrophil biomarkers (e.g., NLR, TAN abundance) show strong predictive value for ICI response and prognosis. Targeting TAN recruitment, polarization, function and NETosis represents a promising strategy to overcome ICI ...
Ying Ning +7 more
wiley +1 more source
Prostaglandin E<sub>2</sub> stimulates opposing effects on inner and outer blood-retina barrier function. [PDF]
Stark AK +6 more
europepmc +1 more source
ABSTRACT Gastrointestinal diseases remain a significant global health concern, primarily due to the limitations of current pharmacological treatments, which often come with adverse side effects and high recurrence rates. This situation highlights the urgent need for safer and more effective alternatives.
Isabel Sousa Alcântara +7 more
wiley +1 more source

