Results 321 to 330 of about 384,482 (373)

Mating behaviors in ovoviviparous black rockfish (Sebastes schlegelii): molecular function of prostaglandin E2 as both a hormone and pheromone. [PDF]

Mar Life Sci Technol
Lyu L, Yao Y, Xie S, Wang X, Wen H, Li Y, Li J, Zuo C, Yan S, Dong J, Qi X.   +10 more
europepmc   +1 more source

Carvacrol Coadministration Ameliorates Lambda‐Cyhalothrin‐Induced Peripheral Neuropathy in Rats: Behavioral and Molecular Evidence

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 7, July 2025.
This study investigates the peripheral neuropathy induced by the pesticide Lambda‐cyhalothrin (CYH) and how carvacrol (CRV) treatment reduces these effects. CYH causes neurological disorders, oxidative stress, and inflammation, while CRV reverses these harmful effects with its antioxidant, anti‐inflammatory, and antiapoptotic properties.
Özge Kandemir, Mustafa İleritürk, Cihan Gür, Nurhan Akaras, Hasan Şimşek, Selçuk Yılmaz, Fatih Mehmet Kandemir   +6 more
wiley   +1 more source

Prostaglandin E₂ regulates senescence and post-senescence neoplastic escape in primary human keratinocytes. [PDF]

Aging (Albany NY)
Srour E, Martin N, Drullion C, De Schutter C, Giroud J, Pioger A, Deslé J, Saas L, Nassour J, Théry J, Decanter G, Penel N, Vercamer C, Salazar-Cardozo C, Abbadie C, Pluquet O.   +15 more
europepmc   +1 more source

Pain Assessment in Osteoarthritis: Present Practices and Future Prospects Including the Use of Biomarkers and Wearable Technologies, and AI‐Driven Personalized Medicine

Journal of Orthopaedic Research, Volume 43, Issue 7, Page 1217-1229, July 2025.
ABSTRACT Osteoarthritis (OA) is a highly prevalent chronic joint disorder affecting ~600 million individuals worldwide and is characterized by complex pain mechanisms that significantly impair patient quality of life. Challenges exist in accurately assessing and measuring pain in OA due to variations in pain perception among individuals and the ...
Shujaa T. Khan, Nick Huffman, Xiaojuan Li, Anukriti Sharma, Carl S. Winalski, Eric T. Ricchetti, Kathleen Derwin, Suneel S. Apte, Daniel Rotroff, Carl Y. Saab, Nicolas S. Piuzzi   +10 more
wiley   +1 more source

Remodeling the immune microenvironment for gastric cancer therapy through antagonism of prostaglandin E2 receptor 4. [PDF]

Genes Dis
Guo M, Hu P, Xie J, Tang K, Hu S, Sun J, He Y, Li J, Lu W, Liu H, Liu M, Yi Z, Peng S.   +12 more
europepmc   +1 more source

Endoplasmic Reticulum Stress in Cancer

MedComm, Volume 6, Issue 7, July 2025.
Persistent ER stress in tumors activates UPR sensors (IRE1α, PERK, ATF6), driving cancer proliferation, metastasis, immune evasion, and drug resistance. This review explores UPR‐mediated signaling crosstalk, angiogenesis, and therapeutic targeting to develop safer anticancer strategies.
Ruixin Zhou, Wenlong Wang, Baizhao Li, Zhu Li, Juan Huang, Xinying Li   +5 more
wiley   +1 more source

The impact of trauma relevant concentrations of prostaglandin E₂ on the anti-microbial activity of the innate immune system. [PDF]

Front Immunol
Nicholson T, Belli A, Lord JM, Hazeldine J.   +3 more
europepmc   +1 more source

Cancer‐Associated Fibroblasts: Heterogeneity, Cancer Pathogenesis, and Therapeutic Targets

MedComm, Volume 6, Issue 7, July 2025.
Cancer‐associated fibroblasts (CAFs) arise from normal fibroblasts in response to various tumor microenvironmental signals, including cytokines such as TGF‐β and IL‐6, paracrine factors like PDGFs, Notch signaling, extracellular vesicles, as well as aging, inflammation, hypoxia, oxidative stress, and increased extracellular matrix (ECM) stiffness. Upon
Yutao Li, Qingyun Liu, Xilin Jing, Yuqi Wang, Xiaohua Jia, Xing Yang, Kezhong Chen   +6 more
wiley   +1 more source

Comparison of the efficacy of aescin and diclofenac sodium in the management of postoperative sequelae and their effect on salivary Prostaglandin E2 and serum C-reactive protein levels after surgical removal of impacted mandibular third molar: a randomized, double-blind, controlled clinical trial. [PDF]

F1000Res
Singhai A, Kambala R, Bhola N.
europepmc   +1 more source