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Prostaglandin E2 on the electroencephalogram
Prostaglandins, 1975Present study was prompted by the report from another center on the occasional occurrence of convulsions and abnormal electroencephalogram (E.E.G.) patterns in women aborted with intra-amniotic prostaglandin F2alpha (PGF2alpha). Fifty four subjects were investigated by means of an E.E.G. taken before and after initiation of PGE2 administration.
J.J. Amy+3 more
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Prostaglandin E2 in Pyloric Stenosis
Archives of Surgery, 1989Prostaglandins are presumed to have many cytoprotective properties that play a role in the pathogenesis of duodenal ulcer and its complications where decreased levels of prostaglandin E2 (PGE2) impair gastric motility, oppose ionic membrane influx, and enhance obstructive changes. These are just some of the mechanisms that may cause pyloric obstruction
Gideon Goldman+6 more
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Pharmacogenetics and Genomics, 2007
Prostaglandin synthesis is the primary target of aspirin and other nonsteroidal antiinflammatory drugs, and thus is a pathway of major interest to pharmacology, pharmacogenetics, and epidemiology. Several lines of evidence implicate prostaglandin E2 in carcinogenesis; this study aimed to identify genetic variants in genes related to prostaglandin E2 ...
Cornelia M. Ulrich+5 more
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Prostaglandin synthesis is the primary target of aspirin and other nonsteroidal antiinflammatory drugs, and thus is a pathway of major interest to pharmacology, pharmacogenetics, and epidemiology. Several lines of evidence implicate prostaglandin E2 in carcinogenesis; this study aimed to identify genetic variants in genes related to prostaglandin E2 ...
Cornelia M. Ulrich+5 more
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Urinary prostaglandin E2 in the newborn and infant
Prostaglandins & Other Lipid Mediators, 2007Prostaglandin E(2) (PGE(2)) belongs to a family of biologically active lipids derived from the 20-carbon essential fatty acids. Renal PGE(2) is involved in the development of the kidney; it also contributes to regulate renal perfusion and glomerular filtration rate, and controls water and electrolyte balance.
Antonucci R+3 more
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Roles of prostaglandin E2 in the cochlea
Hearing Research, 2011Prostaglandins are one of the major groups of chemical mediators in the mammalian body. Among prostaglandins, prostaglandin E2 (PGE2) is the most abundant prostanoid in humans and involved in regulating many different fundamental biological functions. PGE2 signaling is mediated by four distinct E-prostanoid receptors (EPs) namely EP1-4.
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Prostaglandin prodrugs. 5. Prostaglandin E2 ethylene ketal
Journal of Medicinal Chemistry, 1977AbstractProstaglandin E2 (II) wird durch direkte Ketalisierung mit Glykol in Benzol in das Ketal (I) übergeführt und hierdurch seine Dehydratisierung zu Prostaglandin A (III) unterdrückt.
J. J. Biermacher, M. J. Cho, G. L. Bundy
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Dimethylcelecoxib inhibits prostaglandin E2 production
Biochemical Pharmacology, 2008Dimethylcelecoxib (DMC), a derivative of celecoxib, has been developed to distinguish between the COX-dependent and COX-independent anti-carcinogenic effects of celecoxib. Although DMC has been shown to have no COX-inhibitory activity, it is important to ensure that DMC has no other influence on prostaglandin production. Interestingly, in this study we
Wobst, Ivonne+7 more
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Prostaglandin E2 in renal transplant recipients
International Urology and Nephrology, 1992Prostaglandin E2 (PGE2), sodium, potassium and creatinine were determined in the blood and urine of 50 renal transplant recipients treated for at least one year post transplantation with cyclosporine A or azathioprine as immunosuppressive agent. Fourteen healthy subjects were used as a control group.
M M el-Sharabasy, M. M. El-Naggar
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Journal of Endocrinology, 1983
Intravenous injection of 6·7–60 μg of a stable prostaglandin E2 analogue, 16,16-dimethyl prostaglandin E2, into 10-day-old chicks caused profound, long-lasting hypercalcaemia. Simultaneous i.v. loading with 50 μmol Ca/bird enhanced the peak response. The responses were accompanied by sedation and lowered skin temperature.
C. G. Dacke, G. C. Kirby
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Intravenous injection of 6·7–60 μg of a stable prostaglandin E2 analogue, 16,16-dimethyl prostaglandin E2, into 10-day-old chicks caused profound, long-lasting hypercalcaemia. Simultaneous i.v. loading with 50 μmol Ca/bird enhanced the peak response. The responses were accompanied by sedation and lowered skin temperature.
C. G. Dacke, G. C. Kirby
openaire +2 more sources