Results 121 to 130 of about 18,716,571 (404)

Biosíntesis de los productos del ácido araquidónico y su repercusión sobre la inflamación

Revista Cubana de Estomatología, 1998
La liberación de ácido araquidónico o de otros ácidos grasos insaturados de 20 átomos de carbono, el icosatrienoico y el ecosapentanoico, de las reservas hísticas, es la primera fase de la síntesis de las prostaglandinas, tromboxanos y leucotrienos.
Andrés O Pérez Ruiz, . Liulia Cartaya Padrón, Víctor Valencia Fernández, Vivian Sanjurjo Gámez, Teresita Ilisástigui Ortueta   +4 more
doaj  

Pollen allergens do not come alone: pollen associated lipid mediators (PALMS) shift the human immue systems towards a T_H2-dominated response

Allergy, Asthma & Clinical Immunology, 2009
Pollen allergy is characterized by a TH2-biased immune response to pollen-derived allergens. However, pollen-exposed epithelia do not encounter pure allergen but rather a plethora of protein and non-protein substances.
Gilles Stefanie, Mariani Valentina, Bryce Martina, Mueller Martin J, Ring Johannes, Behrendt Heidrun, Jakob Thilo, Traidl-Hoffmann Claudia   +7 more
doaj   +1 more source

Sulforaphane Inhibits Prostaglandin E2 Synthesis by Suppressing Microsomal Prostaglandin E Synthase 1

PLoS ONE, 2012
Sulforaphane (SFN) is a dietary cancer preventive with incompletely characterized mechanism(s) of cancer prevention. Since prostaglandin E2 (PGE2) promotes cancer progression, we hypothesized that SFN may block PGE2 synthesis in cancer cells. We found that SFN indeed blocked PGE2 production in human A549 cancer cells not by inhibiting COX-2, but rather
Jiping Zhou, Denise G Joplin, Janet V Cross, Dennis J Templeton   +3 more
openaire   +4 more sources

Tumor Extracellular Vesicles lncOSLMT Drives Lung Inflammatory Premetastatic Niche Formation in Osteosarcoma via m6A‐Dependent hnRNPA2B1/COX‐2 Axis

Advanced Science, EarlyView.
Tumor‐derived extracellular vesicles program inflammatory lung premetastatic niches through selective delivery of long noncoding RNAs. This work reveals EVs‐associated lncOSLMT as a key driver of lung fibroblast activation via m6A‐dependent PTGS2 stabilization.
Hongbo Li, Zehao Guo, Yutong Zou, Jiongfeng Zhang, Jixiang Shi, Xihong Fu, Jian Tu, Hao Yao, Xuanxuan Lu, Lili Wen, Xianbiao Xie   +10 more
wiley   +1 more source

Enhancement of Orthodontic Tooth Movement by Local Administration of Biofunctional Molecules: A Comprehensive Systematic Review

Pharmaceutics
Enhancement of orthodontic tooth movement (OTM) through local administration of biofunctional molecules has become increasingly significant, particularly for adult patients seeking esthetic and functional improvements.
Cristina Dora Ciobotaru, Dana Feștilă, Elena Dinte, Alexandrina Muntean, Bianca Adina Boșca, Anca Ionel, Aranka Ilea   +6 more
doaj   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Synthesis of tetranor-PGE₁: a urinary metabolite of prostaglandins E₁ and E₂. [PDF]

Tetrahedron Lett, 2020
Kimbrough JR, Jana S, Kim K, Allweil A, Oates JA, Milne GL, Sulikowski GA.   +6 more
europepmc   +1 more source

Prostaglandin E₁Induces c-Fos and Myc Proteins and Protects Rat Hippocampal Cells against Hypoxic Injury [PDF]

, 1994
Hideo Otsuki, Kazuo Yamada, Takamichi Yuguchi, Mamoru Taneda, Tõru Hayakawa   +4 more
openalex   +1 more source

Factor XIII Supplementation in Postpartum Hemorrhage: From Biological Rationale to Clinical Implementation

American Journal of Hematology, EarlyView.
ABSTRACT Postpartum hemorrhage (PPH) remains the leading cause of preventable maternal mortality despite standard interventions. Recent fibrinogen trials failed to improve outcomes, prompting interest in coagulation factor XIII (FXIII). FXIII functions as “molecular cement,” cross‐linking fibrin and stabilizing clots.
Jeremy W. Jacobs, Elizabeth A. Abels, Brian D. Adkins, Garrett S. Booth, Victoria Costa, Sheharyar Raza, Michelle Simon, Jennifer S. Woo, Allison P. Wheeler   +8 more
wiley   +1 more source

Potential Role of Microsomal Prostaglandin E Synthase-1 in Tumorigenesis [PDF]

, 2003
Daisuke Kamei, Makoto Murakami, Yoshihito Nakatani, Yukio Ishikawa, Toshiharu Ishii, Ichiro Kudo   +5 more
openalex   +1 more source