Catalytic mechanism of the primary human prostaglandin F2α synthase, aldo‐keto reductase 1B1 – prostaglandin D2 synthase activity in the absence of NADP(H) [PDF]
Nanae Nagata +4 more
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Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou +6 more
wiley +1 more source
Effects of prostaglandins F-2α and E-2 on cervical extensibility in the late pregnant rat [PDF]
Michael A. Hollingsworth +2 more
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ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani +3 more
wiley +1 more source
Increased formation of 8‐iso‐prostaglandin F2α is associated with altered bone metabolism and lower bone mass in hypercholesterolaemic subjects [PDF]
R. A. Mangiafico +8 more
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Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv +5 more
wiley +1 more source
Intervascular and stimulus selectivity of nitrendipine and related derivatives in KCl and prostaglandin F2α precontracted porcine arteries [PDF]
Georg Kojda +3 more
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Oxytocin-Stimulated Phosphoinositide Hydrolysis and Prostaglandin F Secretion by Luminal Epithelial, Glandular Epithelial, and Stromal Cells from Pig Endometrium. I. Response of Cyclic Pigs on Day 16 Postestrus1 [PDF]
Mehmet Uzumcu +4 more
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THE ACTIONS OF PROSTAGLANDINS E2 AND F2α ON HUMAN FOETAL INTESTINE [PDF]
Stephen L. Hart
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Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source

