Results 181 to 190 of about 50,411 (300)

Seasonal variation in the incidence of central serous chorioretinopathy: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract Central serous chorioretinopathy (CSC) is a chorioretinal disease characterised by serous subretinal fluid (SRF) in the macula, resulting in sudden central vision loss. It predominantly affects working‐age adults, particularly men aged 30 to 60 years.
I. Made Ferdiko Hutamadella, Emil Ørnberg, Mark P. Breazzano, Lasse Jørgensen Cehofski, Chui Ming Gemmy Cheung, Kristina Pfau, M. Cem Sabaner, Lorenzo Ferro Desideri, Camiel J. F. Boon, Yousif Subhi, Elon H. C. van Dijk   +10 more
wiley   +1 more source

Retraction for Murmu et al., Dynamic antagonism between RNA-binding protein CUGBP2 and cyclooxygenase-2-mediated prostaglandin E₂ in radiation damage. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

The Impact of Uterus-Derived Prostaglandins on the Composition of Uterine Fluid During the Period of Conceptus Elongation in Dairy Heifers. [PDF]

Int J Mol Sci
Zhang B, Han Y, Wang S, Cheng M, Yan L, Zhou D, Wang A, Lin P, Jin Y.   +8 more
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Design, synthesis, characterization, biological investigation and docking studies of newly synthesized sulphonyl hydrazide and their derivatives. [PDF]

Sci Rep
Rahman M, Zafar R, Jan MS, Darwish HW, Khattak H, Aschner M, Daglia M, Khan H.   +7 more
europepmc   +1 more source

Design and Synthesis of 13,14-Dihydro Prostaglandin F_1α Analogues as Potent and Selective Ligands for the Human FP Receptor

, 2000
Yili Wang, John A. Wos, Michelle J. Dirr, David L. Soper, Mitchell A. deLong, Glen E. Mieling, Biswanath De, Jack Amburgey, Eric G. Suchanek, Cynthia J. Taylor   +9 more
openalex   +1 more source

Differential segment‐specific signalling pathways for guanylate cyclase C‐activated anion secretion in murine ileocolon

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu, Johannes Reiner, Franz Hofmann, Azam Salari, Ursula Seidler   +4 more
wiley   +1 more source

The Role of Mifepristone in Cervical Maturation and Induction of Labor: A Narrative Review of the Literature. [PDF]

J Clin Med
Toscano FP, D'Angelo M, Giorno A, Gallo A, Piccolo M, Saccone G, Mollo A, Laurelli G.   +7 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source