Results 231 to 240 of about 52,245 (306)

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

Anti-inflammatory and immunomodulatory potential of lignans from Artemisia cina: Integrated quantum, docking, and cytokine expression studies. [PDF]

PLoS One
León Flores MA, López JM, Zavaleta Iglesias SD, Cuéllar-Ordaz JA, de la Cruz-Cruz HA, Nicolás Vázquez MI, Martinez J, Rico GR, González-Ruiz C, López-Arellano ME, Higuera-Piedrahita RI.   +10 more
europepmc   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

Incorporating serial uterine POCUS into routine ICU care for postpartum patients. [PDF]

Indian J Anaesth
Ahmed A, Bandhu D, Sampath S.
europepmc   +1 more source

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

Potential association of cluster headache with certain COVID‐19 vaccines: An assessment from the pharmacovigilance databases

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background The main objective of our study was to assess the potential association between coronavirus disease 2019 (COVID‐19) vaccination and cluster headache (CH) using a pharmacovigilance approach. A secondary objective was to determine whether COVID‐19 vaccines predominantly triggered onset or worsening of the disease.
Elise K. Van Obberghen, Laura Parigny, Nouha Ben‐Othman, Elliot Ewig, Milou‐Daniel Drici, Alexandre O. Gérard, Sophie Gautier, Michel Lanteri‐Minet   +7 more
wiley   +1 more source

The interaction between inflammation and estrogen in adenomyosis : from molecular mechanisms to therapeutic strategies. [PDF]

Semin Immunopathol
Li F, Wang HJ, Zhang Y, Nan FJ, Xu L, Liu ZY, Shi W.   +6 more
europepmc   +1 more source

Diachronic Trends in Dental Hygiene Over the Last 2000 Years in Milan, Italy: An Exploratory Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Background Oral health is a multi‐factorial condition influenced by diet, hygiene and sociocultural habits and its historical evolution can be traced through the bioarchaeological analysis of dento‐skeletal remains, offering unique insights into past lifestyles and public health trends.
Lucie Biehler‐Gomez, Marta Ascoli, Giulia Masini, Maria Claudia Manicone, Dolaji Henin, Claudia Dellavia, Daniela Carmagnola, Alessandro Porro, Cristina Cattaneo, Danilo De Angelis   +9 more
wiley   +1 more source

Author Correction: Serum vitamin D levels and their correlation with pro-inflammatory prostaglandins in Acute myeloid leukemia: a cross-sectional analysis. [PDF]

Sci Rep
Moghaddam HG, Gholami N, Esfahani A, Ghoreishi Z, Khalaji A.   +4 more
europepmc   +1 more source

Clinical and Psychosocial Predisposing Factors Associated With Anaesthesia Failure During Non‐Surgical Root Canal Treatment: A National Dental Practice‐Based Research Network Study

International Endodontic Journal, EarlyView.
ABSTRACT Aim This study aimed to identify dentist, patient, and pre‐treatment clinical characteristics associated with local anaesthesia failure during non‐surgical endodontic treatment. Methodology Data were collected from the National Dental Practice‐Based Research Network study entitled “Predicting Outcomes of Root Canal Treatment (PREDICT)”, which ...
Linda J. Liu, Ronald Ordinola‐Zapata, W. Craig Noblett, Ellen Funkhouser, Alan S. Law, Donald R. Nixdorf, Ernest W. N. Lam, Rahma Mungia, Gregg H. Gilbert, The National Dental Practice‐Based Research Network Collaborative Group   +9 more
wiley   +1 more source