Results 121 to 130 of about 1,807,537 (411)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Evaluation of an EPID in vivo monitoring system using local and external independent audit measurements

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The aim of this work was to evaluate the SunCHECK PerFRACTION, the software for in vivo monitoring using EPID images. Materials/Methods First, the PerFRACTION ability to detect errors was investigated simulating two situations: (1) variation of LINAC output and (2) variation of the phantom thickness.
Samuel Ramalho Avelino, Juliana Rosada Dias, Taís Marques Peron, Gabriel Souza Vidal   +3 more
wiley   +1 more source

Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1 [PDF]

, 2018
Aberrant transforming growth factor–β (TGF-β) signaling is a hallmark of the stromal microenvironment in cancer. Dickkopf-3 (Dkk-3), shown to inhibit TGF-β signaling, is downregulated in prostate cancer and upregulated in the stroma in benign prostatic ...
A Dutta, A Prudova, B Croix St, C Zenzmaier, C Zenzmaier, CL Busceti, CP Goswami, CP Goswami, CY Fu, D Bello-DeOcampo, D Fong, D Romero, D Romero, D Romero, DA Barron, EJ Tokar, Emmanouil Stylianakis, F Abarzua, F Gao, G Ayala, G Untergasser, Giacomo Domenici, GN Thalmann, H Bauderlique-Le Roy, H Kumon, H Kumon, H Ross-Adams, Hoda Kardooni, Ignacio Zabalza, Irantzu Gorroño-Etxebarria, J Debnath, J Veeck, Jennifer H. Steel, JL Leonard, JN Shah, Jonathan Waxman, JP Webber, L Buscemi, LR Rohrschneider, M Augsten, M Bekhouche, M Hangai, M Piva, M Zhu, Maria dM Vivanco, Miriam Rabano, MM Webber, MP Ween, N Fujimoto, N Yu, P Smits, P Su, Robert M. Kypta, S Dennler, T Li, TD Schmittgen, VE Krupnik, Virginia Murillo-Garzón, VP Montecinos, WY Chen, X Wang, Y Gong, Y Kawano, Y Niu, Z Tu, Zainab Al Shareef   +65 more
core   +2 more sources

Prostate Segmentation from Ultrasound Images using Residual Fully Convolutional Network [PDF]

arXiv, 2019
Medical imaging based prostate cancer diagnosis procedure uses intra-operative transrectal ultrasound (TRUS) imaging to visualize the prostate shape and location to collect tissue samples. Correct tissue sampling from prostate requires accurate prostate segmentation in TRUS images.
arxiv  

A Cascaded Residual UNET for Fully Automated Segmentation of Prostate and Peripheral Zone in T2-weighted 3D Fast Spin Echo Images [PDF]

arXiv, 2020
Multi-parametric MR images have been shown to be effective in the non-invasive diagnosis of prostate cancer. Automated segmentation of the prostate eliminates the need for manual annotation by a radiologist which is time consuming. This improves efficiency in the extraction of imaging features for the characterization of prostate tissues. In this work,
arxiv  

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Rapid progression of prostate cancer in men with a BRCA2 mutation. [PDF]

, 2008
Men with BRCA2 mutations have been found to be at increased risk of developing prostate cancer. There is a recent report that BRCA2 carriers with prostate cancer have poorer survival than noncarrier prostate cancer patients.
Ainsworth, Peter, Armel, S, Bellati, Christina, Couch, F, Cummings, S, Daly, Mary, Danquah, Jessica, Domchek, Susan, Eisen, Andrea, Foulkes, WD, Garber, Judy, Ghadirian, P, Gilchrist, Dawna, Hereditary Breast Cancer Study Group, Horsman, Douglas, Isaacs, Claudine, Karlan, Beth, Kim-Sing, Charmaine, Lynch, HT, Manoukian, Siranoush, Maugard, Christine, McKinnon, Wendy, Meschino, Wendy, Nam, R, Narod, SA, Nedelcu, Raluca, Neuhausen, S, Olopade, O, Pasini, Barbara, Poll, A, Saal, H, Stoppa-Lyonnet, D, Sun, P, Tulman, A, Tung, Nadine, Vichodez, G, Wagner, T, Warner, E, Weitzel, J, Wood, Marie   +39 more
core  

Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics [PDF]

, 2012
Background: Lipids have critical functions in cellular energy storage, structure and signaling. Many individual lipid molecules have been associated with the evolution of prostate cancer; however, none of them has been approved to be used as a ...
AA Elgamal, B Brügger, BR Pflug, CG Rogers, Charles Pound, Christina Lynn Addison, D Pchejetski, EF Petricoin, F Bravi, F Teichert, FL Crowe, G Balogh, G Draisma, G Liebisch, H He, HK Min, IM Thompson, IM Thompson, J Ding, J Graessler, J Graessler, J Kurhanewicz, Jeffrey Henegar, Jinghe Mao, JR Graff, Junmei Ai, K Athenstaedt, K Ekroos, K Simons, KA Landers, KH Pietiläinen, KR Keshari, L Zhuang, M Kolak, M Lankinen, M Ollero, Mary R. Roth, MG Swanson, ML Ramírez, O Quehenberger, R Bartz, R Etzioni, R Görke, R Welti, RJ Hamilton, RS Kirby, Ruth Welti, S Devaiah, Steven A. Bigler, TC Gibbs, VD de Mello, VL Freeman, X Han, X Han, X Zhou, Xinchun Zhou, Y Xie, Y Zeng, Youping Deng   +58 more
core   +8 more sources

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source

Novel tumor suppressor microRNA at frequently deleted chromosomal region 8p21 regulates epidermal growth factor receptor in prostate cancer. [PDF]

, 2016
Genomic loss of chromosome (chr) 8p21 region, containing prostate-specific NKX3.1 gene, is a frequent alteration of the prostate cancer (PCa) oncogenome.
Bucay, Nathan, Dahiya, Rajvir, Deng, Guoren, Greene, Kirsten, Majid, Shahana, Saini, Sharanjot, Sekhon, Kirandeep, Shahryari, Varahram, Tabatabai, Z Laura, Tanaka, Yuichiro, Yamamura, Soichiro   +10 more
core   +1 more source