Results 201 to 210 of about 1,476,150 (337)

The future of prostate cancer screening. [PDF]

EClinicalMedicine
eClinicalMedicine.
europepmc   +1 more source

CRISPRa Lipid Nanocomplex‐Mediated Mt3 Targeting Enhances Astrocytic Endocytosis of Amyloid‐β in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
GeTe exhibits intrinsically high carrier concentrations that limit its thermoelectric performance. Herein, CuAgSe alloying synergistically tunes the band structure, induces band flattening and valence‐band convergence, promotes Cu‐ion delocalization, and generates multiscale hierarchical structures to suppress phonon transport.
Junhang Park, Boyoung Kim, Minki Ha, Moonsu Park, Hongji Ryu, Hyerin Yu, Sungsoo Park, Yoon‐Seok Roh, Key‐Hwan Lim, Jin Tae Hong, Sang‐Bae Han, Chun‐Woong Park, Seok‐Beom Yong, Hanseul Park   +13 more
wiley   +1 more source

Phase II trial protocol of focal prostate ablation combined with androgen deprivation therapy for prostate cancer treatment. [PDF]

PLoS One
Koehler J, Lama D, Mendez M, Hsu WW, Oto A, Szmulewitz R, Sidana A.   +6 more
europepmc   +1 more source

Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma

Advanced Science, EarlyView.
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, Jason T. Huse, Bo Chen, Timothy A. Chan, Zengxin Qi, Zhao Zhang, Xiuping Liu, Yuxiang Wang   +16 more
wiley   +1 more source

Reconciling differences in impact of molecular subtyping on response to cisplatin-based chemotherapy

Nature Communications, 2021
Mathieu Roumiguie, Alberto Contreras-Sanz, Gunjan Kumar, Peter C. Black   +3 more
doaj   +1 more source

Cellular Immunotherapy for Prostate Cancer: Lessons Learned From 15 Years of Sipuleucel-T. [PDF]

Prostate Cancer
Shore ND, Antonarakis ES, Hafron J, Moses KA, Pieczonka C, Lowentritt B, Sheikh N, George DJ, Dorff TB.   +8 more
europepmc   +1 more source

Active Surveillance in Younger Men With Prostate Cancer

, 2017
Michael S. Leapman, Janet E. Cowan, Hao G. Nguyen, Katsuto Shinohara, Nannette Perez, Matthew R. Cooperberg, William J. Catàlona, Peter R. Carroll   +7 more
openalex   +2 more sources

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

FOXA1 Alterations in Prostate Cancer: Expression, Mutation Classes, and Copy Number Changes. [PDF]

In Vivo
Lehrer S, Rheinstein P.
europepmc   +1 more source

MiR-34a affects G2 arrest in prostate cancer PC3 cells via Wnt pathway and inhibits cell growth and migration.

, 2020
Bo Dong, Xu Gc, Liu St, Liu T, Bin Geng
openalex   +2 more sources